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Merck
CN

73763

Nicotinic acid

for inorganic trace analysis, ≥99.999% (metals basis)

Synonym(s):

3-Picolinic acid, Niacin, Pellagra preventive factor, Pyridine-3-carboxylic acid, Vitamin B3

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About This Item

Empirical Formula (Hill Notation):
C6H5NO2
CAS Number:
Molecular Weight:
123.11
UNSPSC Code:
12352200
NACRES:
NA.24
PubChem Substance ID:
EC Number:
200-441-0
Beilstein/REAXYS Number:
109591
MDL number:
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Quality Level

assay

≥99.5% (HPLC), ≥99.999% (metals basis)

form

powder

color

colorless to white

mp

236-239 °C (lit.)

SMILES string

OC(=O)c1cccnc1

cation traces

Ag: ≤0.02 mg/kg, Al: ≤0.1 mg/kg, As: ≤0.05 mg/kg, Au: ≤0.01 mg/kg, Ba: ≤0.05 mg/kg, Be: ≤0.01 mg/kg, Bi: ≤0.01 mg/kg, Ca: ≤2 mg/kg, Cd: ≤0.01 mg/kg, Ce: ≤0.01 mg/kg, Co: ≤0.01 mg/kg, Cr: ≤0.2 mg/kg, Cs: ≤0.01 mg/kg, Cu: ≤0.02 mg/kg, Dy: ≤0.01 mg/kg, Er: ≤0.01 mg/kg, Eu: ≤0.01 mg/kg, Fe: ≤0.5 mg/kg, Ga: ≤0.01 mg/kg, Gd: ≤0.01 mg/kg, Ge: ≤0.01 mg/kg, Hf: ≤0.01 mg/kg, Hg: ≤0.005 mg/kg, Ho: ≤0.01 mg/kg, In: ≤0.01 mg/kg, Ir: ≤0.01 mg/kg, K: ≤0.2 mg/kg, La: ≤0.01 mg/kg, Li: ≤0.01 mg/kg, Lu: ≤0.01 mg/kg, Mg: ≤0.05 mg/kg, Mn: ≤0.01 mg/kg, Mo: ≤0.01 mg/kg, Na: ≤0.5 mg/kg, Nb: ≤0.01 mg/kg, Nd: ≤0.01 mg/kg, Ni: ≤0.05 mg/kg, Os: ≤0.01 mg/kg, Pb: ≤0.01 mg/kg, Pd: ≤0.01 mg/kg, Pr: ≤0.01 mg/kg, Pt: ≤0.05 mg/kg, Rb: ≤0.01 mg/kg, Re: ≤0.01 mg/kg, Rh: ≤0.01 mg/kg, Ru: ≤0.01 mg/kg, Sb: ≤0.01 mg/kg, Sc: ≤0.05 mg/kg, Se: ≤0.05 mg/kg, Sm: ≤0.01 mg/kg, Sn: ≤0.01 mg/kg, Sr: ≤0.01 mg/kg, Ta: ≤0.01 mg/kg, Tb: ≤0.01 mg/kg, Te: ≤0.01 mg/kg, Th: ≤0.01 mg/kg, Ti: ≤0.05 mg/kg, Tl: ≤0.01 mg/kg, Tm: ≤0.01 mg/kg, U: ≤0.01 mg/kg, V: ≤0.01 mg/kg, W: ≤0.01 mg/kg, Y: ≤0.01 mg/kg, Yb: ≤0.01 mg/kg, Zn: ≤0.1 mg/kg, Zr: ≤0.01 mg/kg

InChI

1S/C6H5NO2/c8-6(9)5-2-1-3-7-4-5/h1-4H,(H,8,9)

InChI key

PVNIIMVLHYAWGP-UHFFFAOYSA-N

General description

Nicotinic acid is a water soluble B complex vitamin, with effective plasma lipid-lowering effect and hence is clinically used to treat hyperlipidemia.


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pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Eye Irrit. 2

Storage Class

13 - Non Combustible Solids

wgk

WGK 1

flash_point_f

379.4 °F - closed cup

flash_point_c

193 °C - closed cup

Regulatory Information

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Molecular identification of nicotinic acid receptor
Soga T, et al.
Biochemical and biophysical research communications, 303(1), 364-369 (2003)
Sorin Tunaru et al.
Nature medicine, 9(3), 352-355 (2003-02-04)
Nicotinic acid (niacin), a vitamin of the B complex, has been used for almost 50 years as a lipid-lowering drug. The pharmacological effect of nicotinic acid requires doses that are much higher than those provided by a normal diet. Its