2-Imidazolidinethione-4,4,5,5-d₄

2-Imidazolidinethione-4,4,5,5-d₄ is an isotope labeled analog of the fungicide metabolite 2-imidazolidinethione, wherein the imidazoline ring C-4 and C-5 protons are replaced by deuterium.

Isotope-labeled compounds are increasingly used in isotope dilution mass spectrometry (IDMS) for the quantitative analysis of pesticides. The major advantage of using this technique is that the isotope-labeled compounds have nearly the same physical properties as their non-labeled counterpart analogs, and thus show identical behavior during the workup and sample preparation process. This helps in overcoming the problems of matrix effects generally encountered in the usual LC-MS/GC-MS analysis, potentially resulting in biased results. By spiking the sample before workup with its isotope labeled analog, the loss of analyte that leads to matrix effects can be determined and compensated.

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