Skip to Content
Merck
CN

74309

Padimate O

analytical standard

Synonym(s):

2-Ethylhexyl 4-(dimethylamino)benzoate

Sign In to View Organizational & Contract Pricing.

Select a Size

About This Item

Linear Formula:
(CH3)2NC6H4CO2CH2CH(C2H5)(CH2)3CH3
CAS Number:
21245-02-3
Molecular Weight:
277.40
NACRES:
NA.24
PubChem Substance ID:
329765613
UNSPSC Code:
41116107
EC Number:
244-289-3
MDL number:
MFCD00017526

Key Documents

View All Documentation
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

InChI key

WYWZRNAHINYAEF-UHFFFAOYSA-N

InChI

1S/C17H27NO2/c1-5-7-8-14(6-2)13-20-17(19)15-9-11-16(12-10-15)18(3)4/h9-12,14H,5-8,13H2,1-4H3

SMILES string

CCCCC(CC)COC(=O)c1ccc(cc1)N(C)C

grade

analytical standard

assay

≥98.0% (HPLC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

refractive index

n20/D 1.541±0.001, n20/D 1.542 (lit.)

bp

325 °C (lit.)

density

0.995 g/mL at 25 °C (lit.)

application(s)

cleaning products
cosmetics
environmental
food and beverages
personal care

format

neat

Quality Level

100

Looking for similar products? Visit Product Comparison Guide

General description

Padimate O is a tertiary amine derivative of p-aminobenzoic acid (PABA), which is commonly used as a sunscreen agent in cosmetics and other sunscreen formulations due to its ability to absorb ultraviolet radiations.

Application

Padimate O may be used as a reference standard in the determination of padimate O in cosmetics using high performance liquid chromatography (HPLC).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

pictograms

Health hazard
GHS08

signalword

Danger

hcodes

H360FD

Hazard Classifications

Repr. 1B

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 2

flash_point_f

374.0 °F - closed cup

flash_point_c

190 °C - closed cup

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
BCCD8748
BCBZ8379
BCBV2153
BCBQ9627V

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Assay of mixtures of padimate-O and oxybenzone in sunscreen formulations by high-performance liquid chromatography.
Tan ISH, et al.
Journal of Chromatography A, 291, 275-282 (1984)
R Bestak et al.
The Journal of investigative dermatology, 105(3), 345-351 (1995-09-01)
This study compares the ability of two ultraviolet (UV) B-absorbing sunscreens, 2-ethylhexyl p-methoxycinnamate (2-EHMC) and 2-ethylhexyl p-aminobenzoate (Padimate O), and two physical sunscreens, microfine titanium dioxide (MTD) and zinc oxide, to protect the skin immune system from chronic (4 weeks)
V C Dunkel et al.
Environmental and molecular mutagenesis, 20(3), 188-198 (1992-01-01)
The nitrosamine contaminant, N-nitroso-N-methyl-p-aminobenzoic acid, 2-ethylhexyl ester (NPABAO), of the major sunscreen ingredient Padimate O (4-N,N'-dimethylamino-benzoic acid, 2-ethylhexyl ester) was synthesized and tested for mutagenicity in the Salmonella typhimurium and mouse lymphoma L5178Y TK +/- assays. In contrast to the
S H Dromgoole et al.
Journal of the American Academy of Dermatology, 22(6 Pt 1), 1068-1078 (1990-06-01)
Reports in the literature of sensitization associated with many commonly used sunscreening agents including p-aminobenzoic acid (PABA), PABA derivatives, anthranilates, salicylates, cinnamates, benzophenones, and dibenzoylmethane derivatives are reviewed. Several of these case reports involved subjects with various photodermatoses, implicating enhanced
M Gulston et al.
Mutation research, 444(1), 49-60 (1999-09-08)
On illumination with simulated sunlight, the UVB-absorbing sunscreen chemical 2-ethylhexyl-4-dimethylaminobenzoate (Padimate-O) generates excited species which inflict non-ligatable strand breaks on DNA in vitro and it also becomes mutagenic to yeast in vivo. Padimate-O is known to penetrate human skin but
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service