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Merck
CN

74412

Trolamine salicylate

analytical standard

Synonym(s):

TEA salicylate, Triethanolamine salicylate, Triethanolaminium salicylate, Tris(2-hydroxyethyl)ammonium 2-hydroxybenzoate

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About This Item

Empirical Formula (Hill Notation):
C13H21NO6
CAS Number:
Molecular Weight:
287.31
UNSPSC Code:
41116107
NACRES:
NA.24
EC Number:
218-531-3
Beilstein/REAXYS Number:
7451205
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InChI key

UEVAMYPIMMOEFW-UHFFFAOYSA-N

InChI

1S/C7H6O3.C6H15NO3/c8-6-4-2-1-3-5(6)7(9)10;8-4-1-7(2-5-9)3-6-10/h1-4,8H,(H,9,10);8-10H,1-6H2

SMILES string

OCC[NH+](CCO)CCO.Oc1ccccc1C([O-])=O

grade

analytical standard

assay

≥98.0% (HPLC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

cleaning products
cosmetics
environmental
food and beverages
personal care

format

neat

Quality Level

General description

Trolamine salicylate is a type of salicylate derivative, which is a sunscreen agent and a topical analgesic.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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P Morra et al.
The Annals of pharmacotherapy, 30(9), 935-940 (1996-09-01)
To compare the rate and extent of systemic salicylate absorption following single and multiple applications of two topically applied analgesics, one containing methyl salicylate and the other containing trolamine salicylate. Two-period, two-treatment, randomized, crossover, multiple-dose study in healthy men and
A Babar et al.
Pharmaceutica acta Helvetiae, 66(12), 322-328 (1991-01-01)
Recently, triethanolamine salicylate (TEAS) is frequently being incorporated in several over-the-counter topical analgesic pharmaceutical products. Since the clinical efficacy of such dosage form depends upon the release of the active ingredient at the site of application, the present study was
Trolamine salicylate cream in osteoarthritis.
JAMA, 248(13), 1577-1578 (1982-10-01)
C D Ciccone et al.
Physical therapy, 71(9), 666-675 (1991-09-01)
The purpose of this study was to determine the effects of ultrasound and phonophoresis using an anti-inflammatory-analgesic cream (trolamine salicylate) on delayed-onset muscle soreness (DOMS). Repeated eccentric contractions were used to induce DOMS in the elbow flexors of 40 college-aged
Brian G Ragan et al.
Medicine and science in sports and exercise, 39(11), 1942-1948 (2007-11-08)
Analgesic balms (AB) are widely used in sports medicine. We previously have examined effects of various counterirritant-based AB on pressor responses evoked by muscular contraction (MC), mediated by group III and IV muscle afferents known to produce exercise and nociceptive

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