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Merck
CN

74412

Supelco

Trolamine salicylate

analytical standard

Synonym(s):

TEA salicylate, Triethanolamine salicylate, Triethanolaminium salicylate, Tris(2-hydroxyethyl)ammonium 2-hydroxybenzoate

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About This Item

Empirical Formula (Hill Notation):
C13H21NO6
CAS Number:
2174-16-5
Molecular Weight:
287.31
Beilstein:
7451205
EC Number:
218-531-3
UNSPSC Code:
41116107
NACRES:
NA.24

Key Documents

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grade

analytical standard

Quality Level

100

Assay

≥98.0% (HPLC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

cleaning products
cosmetics
environmental
food and beverages
personal care

format

neat

SMILES string

OCC[NH+](CCO)CCO.Oc1ccccc1C([O-])=O

InChI

1S/C7H6O3.C6H15NO3/c8-6-4-2-1-3-5(6)7(9)10;8-4-1-7(2-5-9)3-6-10/h1-4,8H,(H,9,10);8-10H,1-6H2

InChI key

UEVAMYPIMMOEFW-UHFFFAOYSA-N

General description

Trolamine salicylate is a type of salicylate derivative, which is a sunscreen agent and a topical analgesic.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302,H315,H319,H335

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
BCCG5443
BCCC0314
BCBV6072

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Pharmacotherapeutics in Medical Disorders (2012)
R E Davis et al.
Archives of facial plastic surgery, 1(1), 27-32 (2000-08-11)
To determine the efficacy of topical anti-ischemic drug therapy in the salvage of failing, random-pattern skin flaps. Prospective, randomized, placebo-controlled, therapeutic trial. Academic medical center. Sixty-one adult male Sprague-Dawley rats. Each experimental rat underwent a caudally based random-pattern skin flap
A Babar et al.
Pharmaceutica acta Helvetiae, 66(12), 322-328 (1991-01-01)
Recently, triethanolamine salicylate (TEAS) is frequently being incorporated in several over-the-counter topical analgesic pharmaceutical products. Since the clinical efficacy of such dosage form depends upon the release of the active ingredient at the site of application, the present study was
S E Cross et al.
Pharmaceutical research, 16(3), 427-433 (1999-04-23)
To determine how changes in cutaneous blood flow induced in-vivo by methylsalicylate (MeSA), compared to non-rubefacient triethanolamine salicylate (TSA), affected topical salicylate absorption and distribution, and to assess formulation therapeutic potential by comparing tissue concentrations to published antiinflammatory concentrations. Flux
C D Ciccone et al.
Physical therapy, 71(9), 666-675 (1991-09-01)
The purpose of this study was to determine the effects of ultrasound and phonophoresis using an anti-inflammatory-analgesic cream (trolamine salicylate) on delayed-onset muscle soreness (DOMS). Repeated eccentric contractions were used to induce DOMS in the elbow flexors of 40 college-aged
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