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74777

Astragaloside IV

>98.0%

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About This Item

Empirical Formula (Hill Notation):
C41H68O14
CAS Number:
84687-43-4
Molecular Weight:
784.97
NACRES:
NA.85
PubChem Substance ID:
329765850
UNSPSC Code:
41106200
MDL number:
MFCD16036240
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Quality Level

100

assay

≥98.0% (TLC), >98.0%

form

powder

SMILES string

CC(C)(O)[C@@H]1CC[C@@](C)(O1)[C@H]2[C@@H](O)C[C@@]3(C)[C@@H]4C[C@H](O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)[C@H]6C(C)(C)[C@H](CC[C@@]67C[C@@]47CC[C@]23C)O[C@@H]8OC[C@@H](O)[C@H](O)[C@H]8O

InChI

1S/C41H68O14/c1-35(2)24(54-33-29(48)26(45)20(44)17-51-33)9-11-41-18-40(41)13-12-37(5)31(39(7)10-8-25(55-39)36(3,4)50)19(43)15-38(37,6)23(40)14-21(32(35)41)52-34-30(49)28(47)27(46)22(16-42)53-34/h19-34,42-50H,8-18H2,1-7H3/t19-,20+,21-,22+,23-,24-,25-,26-,27+,28-,29+,30+,31-,32-,33-,34+,37+,38-,39+,40-,41+/m0/s1

InChI key

QMNWISYXSJWHRY-YLNUDOOFSA-N

Biochem/physiol Actions

Anti-inflammatory.

Other Notes

Chemical constituent of Astragali radix

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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
BCCP1388
BCCB3090
BCCB2207
BCBX5957
BCBS9602V

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I. Kitagawa et al.
Chemical & Pharmaceutical Bulletin, 31, 698-698 (1983)
Wenya Shan et al.
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 37(1), 85-88 (2012-06-30)
To provide a scientific basis for the drug-combination and aim to examine whether astragaloside IV has the impact on the cytochrome P450 enzymes. Tolbutamide, chlorzoxazone, coumarin, nifedipine, and phenacetin were as probe substrates of rat CYP2C9, CYP2E1, CYP2A6, CYP3A4, and
Ming Hao et al.
Zhonghua yi xue za zhi, 92(30), 2104-2107 (2012-11-20)
To explore the protective effects of astragaloside IV on retinal ganglion cells (RGC) incubated under high glucose. Cultured RGC-5 were divided into 3 groups: control, high glucose and high glucose+astragaloside IV. The survival rate of cell was measured by CCK-8
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Global Trade Item Number

SKUGTIN
74777-1MG04061832891781