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Merck
CN

75110

Phyllanthin

analytical standard

Synonym(s):

(2S,3S)-(+)-1,4-Dimethoxy-2,3-diveratrylbutane

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About This Item

Empirical Formula (Hill Notation):
C24H34O6
CAS Number:
Molecular Weight:
418.52
UNSPSC Code:
85151701
NACRES:
NA.24
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
2066503
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grade

analytical standard

Quality Level

assay

≥95.0% (HPLC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

food and beverages

format

neat

SMILES string

COC[C@@H](Cc1ccc(OC)c(OC)c1)[C@@H](COC)Cc2ccc(OC)c(OC)c2

InChI

1S/C24H34O6/c1-25-15-19(11-17-7-9-21(27-3)23(13-17)29-5)20(16-26-2)12-18-8-10-22(28-4)24(14-18)30-6/h7-10,13-14,19-20H,11-12,15-16H2,1-6H3/t19-,20-/m1/s1

InChI key

KFLQGJQSLUYUBF-WOJBJXKFSA-N

General description

Phyllanthin is found in many Phyllanthus species. It is a lignan compound which exhibits various biochemical and pharmacological properties.

Application

Phyllanthin may be used as a reference standard for the determination of the analyte in Phyllanthus species by high-performance thin layer chromatography (HPTLC).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Other Notes

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.


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Storage Class

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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Quantitative determination of phyllanthin and hypophyllanthin in Phyllanthus species by high-performance thin layer chromatography.
Tripathi AK, et al.
Phytochemical Analysis, 17(6), 394- 397 (2006)
Phyllanthin from Phyllanthus amarus inhibits cellular and humoral immune responses in Balb/C mice.
Ilangkovan M, et al.
Phytomedicine, 23(12), 1441- 1450 (2016)
Protective activity of phyllanthin in ethanol-treated primary culture of rat hepatocytes.
Chirdchupunseree H and Pramyothin P
Journal of Ethnopharmacology, 128(1), 172- 176 (2010)