75256
Synephrine
analytical standard
Synonym(s):
1-(4-Hydroxyphenyl)-2-methylaminoethanol, 4-Hydroxy-α-(methylaminomethyl)benzyl alcohol
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About This Item
Empirical Formula (Hill Notation):
C9H13NO2
CAS Number:
Molecular Weight:
167.21
PubChem Substance ID:
UNSPSC Code:
85151701
NACRES:
NA.24
EC Number:
202-300-9
MDL number:
grade
analytical standard
assay
≥98.0% (HPLC)
shelf life
limited shelf life, expiry date on the label
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
impurities
≤12.0% water (Karl Fischer)
application(s)
food and beverages
format
neat
storage temp.
2-8°C
InChI
1S/C9H13NO2/c1-10-6-9(12)7-2-4-8(11)5-3-7/h2-5,9-12H,6H2,1H3
InChI key
YRCWQPVGYLYSOX-UHFFFAOYSA-N
General description
Synephrine is a sympathomimetic amine from the plant Citrus aurantium and is identified as a major active component of dietary supplements.
Application
Synephrine may be used as a reference standard for the determination of synephrine in dietary supplements using high-performance liquid chromatography with acidic potassium permanganate chemiluminescence detection.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Analysis Note
identification (GC-MS): identity conforms
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signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Determination of synephrine in weight-loss products using high performance liquid chromatography with acidic potassium permanganate chemiluminescence detection.
Slezak T, et al.
Analytica Chimica Acta, 593(1), 98-102 (2007)
Ischemic stroke associated with use of an ephedra-free dietary supplement containing synephrine.
Bouchard CN, et al.
Mayo Clinic Proceedings. Mayo Clinic, 80(4), 541-545 (2005)
Sidney J Stohs et al.
International journal of medical sciences, 9(7), 527-538 (2012-09-20)
This review summarizes the published as well as unpublished human studies involving Citrus aurantium (bitter orange) extract and its primary protoalkaloid p-synephrine, providing information and an assessment of the safety and efficacy of these widely used products. The results of
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 342521-1G | 04061836684587 |
| 342521-25G | 04061831819809 |
| 342521-5G | 04061836684594 |