75769
Ethylparaben
pharmaceutical secondary standard; traceable to USP and PhEur
Synonym(s):
Ethyl 4-hydroxybenzoate, Ethylparaben
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About This Item
Linear Formula:
HOC6H4CO2C2H5
CAS Number:
Molecular Weight:
166.17
EC Number:
204-399-4
UNSPSC Code:
41116000
eCl@ss:
39024522
Beilstein/REAXYS Number:
1101972
MDL number:
InChI key
NUVBSKCKDOMJSU-UHFFFAOYSA-N
InChI
1S/C9H10O3/c1-2-12-9(11)7-3-5-8(10)6-4-7/h3-6,10H,2H2,1H3
SMILES string
CCOC(=O)c1ccc(O)cc1
agency
traceable to Ph. Eur. E2425000, traceable to USP 1267000
bp
297-298 °C (lit.)
storage temp.
2-8°C
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Joseph C White et al.
Journal of biomedical materials research. Part A, 101(2), 438-446 (2012-08-07)
Perfluorocarbons (PFCs) are used in biomaterial formulations to increase oxygen (O(2) ) tension and create a homogeneous O(2) environment in three-dimensional tissue constructs. It is unclear how PFCs affect mechanical and transport properties of the scaffold, which are critical for
Zheng Cai et al.
AAPS PharmSciTech, 12(4), 1102-1109 (2011-09-01)
Gastrodin is the major bioactive constituent of the traditional Chinese drug "Tianma." It is used in the treatment of some nervous system diseases and can be transported to the brain via intranasal administration. In the current paper, the development of
Shinshi Oishi
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 42(11), 1845-1849 (2004-09-08)
Parabens are alkyl esters of p-hydroxybenzoic acid widely used as preservatives in foodstuffs, cosmetics toiletries and pharmaceuticals. These compounds are known to exert a weak estrogenic activity in estrogen receptor assays in vitro. In addition butyl and propyl parabens show
Nikhil M Vad et al.
Journal of pharmaceutical sciences, 97(5), 1934-1945 (2007-09-12)
The metabolism and toxicity of ethyl 4-hydroxybenzoate (4-HEB) were investigated in vitro using tyrosinase enzyme, a melanoma molecular target, and CYP2E1 induced rat liver microsomes, and in human SK-MEL-28 melanoma cells. The results were compared to 4-hydroxyanisole (4-HA). At 90
Suzanne Abbas et al.
Drug metabolism and pharmacokinetics, 25(6), 568-577 (2010-10-12)
Parabens (alkyl esters of 4-hydroxybenzoic acid) are widely used as preservatives in drugs, cosmetic products, and foodstuffs. Safety concerns have recently increased due to the potential health risks associated to exposure to large amounts of these substances. Biotransformation of parabens
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