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Merck
CN

75965

Oxytetracycline dihydrate

≥98.0% (NT)

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About This Item

Empirical Formula (Hill Notation):
C22H24N2O9 · 2H2O
CAS Number:
Molecular Weight:
496.46
UNSPSC Code:
51101500
MDL number:
Beilstein/REAXYS Number:
2714587
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assay

≥98.0% (NT)

optical activity

[α]20/D −195±3°, c = 1% in 0.1 M HCl

mp

182-186 °C (dec.)

application(s)

agriculture
environmental

mode of action

protein synthesis | interferes

SMILES string

[H]O[H].[H]O[H].CN(C)[C@H]1C2[C@@H](O)C3C(=C(O)[C@]2(O)C(=O)C(C(N)=O)=C1O)C(=O)c4c(O)cccc4[C@@]3(C)O

General description

Chemical structure: tetracycline

Biochem/physiol Actions

Antibiotic produced by Streptomyces rimosus.
Mode of Action: Inhibits protein synthesis (elongation) by preventing binding of aminoacyl-tRNA to the 30S subunit.
Antimicrobial spectrum: Gram-negative and Gram-positive bacteria.
Mode of Resistance: Active efflux, ribosome protection, tetracycline inactivation.




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