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Merck
CN

76850

1,2,2,6,6-Pentamethylpiperidine

purum, ≥99.0% (GC)

Synonym(s):

PMP, Pempidine

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About This Item

Empirical Formula (Hill Notation):
C10H21N
CAS Number:
Molecular Weight:
155.28
EC Number:
201-211-2
UNSPSC Code:
12352100
PubChem Substance ID:
Beilstein/REAXYS Number:
103806
MDL number:
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InChI key

XULIXFLCVXWHRF-UHFFFAOYSA-N

InChI

1S/C10H21N/c1-9(2)7-6-8-10(3,4)11(9)5/h6-8H2,1-5H3

SMILES string

CN1C(C)(C)CCCC1(C)C

grade

purum

assay

≥99.0% (GC)

bp

187-188 °C (lit.)

density

0.858 g/mL at 25 °C (lit.)

Other Notes

One of the most strongly basic tertiary amines (sterically hindered and nonquaternizing)

pictograms

FlameSkull and crossbones

signalword

Danger

Hazard Classifications

Acute Tox. 3 Oral - Eye Irrit. 2 - Flam. Liq. 3 - Skin Irrit. 2 - STOT SE 3

Storage Class

3 - Flammable liquids

wgk

WGK 3

flash_point_f

131.0 °F - closed cup

flash_point_c

55 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

Regulatory Information

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H.Z. Sommer et al.
The Journal of Organic Chemistry, 36, 824-824 (1971)
[Tuberculous osteoarthritis revealed by ankle injury].
O Louletzian et al.
Presse medicale (Paris, France : 1983), 28(10), 531-532 (1999-04-21)
M L Kemel et al.
Neuroscience, 50(3), 597-610 (1992-10-01)
Previously, using a new in vitro microsuperfusion procedure, we have demonstrated marked differences in the cholinergic presynaptic regulation of the release of [3H]dopamine continuously synthesized from [3H]tyrosine in two close striosomal- and matrix-enriched areas of the cat caudate nucleus. A
L Tremblay et al.
Proceedings of the National Academy of Sciences of the United States of America, 89(23), 11214-11218 (1992-12-01)
Using a sensitive in vitro microperfusion method, the effects of selective and potent agonists of NK1, NK2, and NK3 tachykinin receptors ([Pro9]SP, ([Lys5,MeLeu9,Nle10]NKA-(4-10), and [Pro7]NKB, respectively) on the presynaptic control of dopamine release were investigated in striosomal-enriched (area rich in
T J Martin et al.
The Journal of pharmacology and experimental therapeutics, 254(1), 45-51 (1990-07-01)
The nature of mecamylamine's and pempidine's antagonism of nicotine in the central nervous system has not been defined clearly. Although these compounds are thought to be noncompetitive antagonists in the brain due to the fact that they do not compete

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