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Merck
CN

77662

Hypoxanthine

Synonym(s):

Hypoxanthine, 6-Hydroxypurine

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About This Item

Empirical Formula (Hill Notation):
C5H4N4O
CAS Number:
Molecular Weight:
136.11
EC Number:
200-697-3
UNSPSC Code:
12352200
NACRES:
NA.21
Beilstein/REAXYS Number:
5811
MDL number:
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biological source

synthetic

Quality Level

assay

≥99.0% (HPLC), 98.0-101.0% (wt%, HClO4 1M, NT)

form

powder

impurities

≤2 wt. % water, ≤20 mg/kg heavy metals, ≤5000 mg/kg residual solvents (acetone) (GLC-HS), ≤5000 mg/kg residual solvents (isopropanol) (GLC-HS)

suitability

suitable for manufacturing use

SMILES string

O=C1NC=Nc2nc[nH]c12

InChI

1S/C5H4N4O/c10-5-3-4(7-1-6-3)8-2-9-5/h1-2H,(H2,6,7,8,9,10)

InChI key

FDGQSTZJBFJUBT-UHFFFAOYSA-N

Application

Hypoxanthine is a nutrient additive for a variety of cell culture applications involving bacterial, parasite (Plasmodium falciparum) and animal cells. Hypoxanthine is a component of selection media used in hybridoma technologies.


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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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Chien-Wei Hou et al.
The American journal of Chinese medicine, 40(5), 979-991 (2012-08-30)
Hyperuricemia causes gouty arthritis, kidney disease, heart disease, and other diseases. Xanthine oxidase (XOD) and urate transporters play important roles in urate homeostasis. Numerous plants have been identified as XOD inhibitors. Longan seeds are known to contain high levels of
Tomáš Tichý et al.
European journal of medicinal chemistry, 55, 307-314 (2012-08-04)
Hexadecyloxypropyl esters of acyclic nucleoside phosphonates containing guanine (G) or hypoxanthine (Hx) and a (S)-[3-hydroxy-2-(phosphonomethoxy)propyl] [(S)-HPMP] or 2-(2-phosphonoethoxy)ethyl (PEE) acyclic moiety have been prepared. The activity of the prodrugs was evaluated in vitro against different virus families. Whereas ester derivatives of
Abdulazeez T Lawal et al.
Food chemistry, 135(4), 2982-2987 (2012-09-18)
A potentiometric enzyme electrode for detection of hypoxanthine (Hx) in fish meat is described. The sensor was developed by entrapment of xanthine oxidase (XOD) and ferrocene carboxylic acid (Fc) into polypyrrole (PPy) film during galvanostatic polymerisation film formation. The responses



Global Trade Item Number

SKUGTIN
77662-100G04061832763040
77662-25G04061833365588