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Merck
CN

78560

N-Phenylglycine

purum, ≥97.0% (T)

Synonym(s):

(Phenylamino)acetic acid, Anilinoacetic acid

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About This Item

Linear Formula:
C6H5NHCH2COOH
CAS Number:
Molecular Weight:
151.16
EC Number:
203-070-2
UNSPSC Code:
12352200
PubChem Substance ID:
Beilstein/REAXYS Number:
509838
MDL number:
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InChI key

NPKSPKHJBVJUKB-UHFFFAOYSA-N

InChI

1S/C8H9NO2/c10-8(11)6-9-7-4-2-1-3-5-7/h1-5,9H,6H2,(H,10,11)

SMILES string

OC(=O)CNc1ccccc1

grade

purum

assay

≥97.0% (T)

form

powder or crystals

color

faintly yellow to yellow

mp

121-123 °C (lit.), 121-125 °C

application(s)

detection
peptide synthesis

Storage Class

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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J M Janusz et al.
Journal of medicinal chemistry, 33(3), 1052-1061 (1990-03-01)
Twenty esters of L-aspartyl-D-phenylglycine, as well as two substituted analogues, an o-fluoro and a p-hydroxy-phenylglycine ester, were prepared. The L-aspartyl-D-phenylglycine (-)-alpha- and (+)-beta-fenchyl esters had the highest sweetness potency at 1200 and 3700 times that of sucrose, respectively. The high
R E Webb et al.
Journal of dental research, 70(3), 211-214 (1991-03-01)
Three structurally related substituted amino acids (N-compounds) were studied in a three-step dentin-bonding protocol. The first step of an acidic ferric oxalate solution and the third step of a surface-active comonomer were held constant throughout the study. In the second
G E Schumacher et al.
Journal of dental research, 76(1), 602-609 (1997-01-01)
Effective composite-to-dentin bonding has been achieved by the sequential use of dilute aqueous nitric acid (HNO3) and acetone solutions of N-phenylglycine and a carboxylic acid monomer, e.g., p-PMDM. Both the HNO3 pre-treatment and the surface-initiated polymerization that results from reaction
Rheem A Totah et al.
Biochemistry, 43(24), 7907-7914 (2004-06-16)
Horseradish peroxidase (HRP) typically oxidizes aniline derivatives using hydrogen peroxide as the oxidant. The action of HRP on N-alkyl-N-phenylglycine derivatives 1b-1e (PhN(R)CH(2)COOH; R = Me, Et, n-Pr, i-Pr, respectively) is highly unusual if not unique. Under standard peroxidatic conditions (HRP/H(2)O(2)/air)
Y Imai et al.
Dental materials : official publication of the Academy of Dental Materials, 10(4), 275-277 (1994-07-01)
This research was designed to study the effect of water or carboxylic acid monomer on the polymerization of 2-hydroxyethyl methacrylate (HEMA) in order to understand the bonding mechanism of dentin bonding systems using N-phenylglycine (NPG). The polymerization of HEMA in

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