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Merck
CN

78580

DL-α-Phenylglycine

purum, ≥98.0% (NT)

Synonym(s):

(±)-α-Aminophenylacetic acid

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About This Item

Linear Formula:
C6H5CH(NH2)COOH
CAS Number:
Molecular Weight:
151.16
UNSPSC Code:
12352200
PubChem Substance ID:
EC Number:
220-608-1
Beilstein/REAXYS Number:
3197862
MDL number:
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SMILES string

CC(C)(C)OC(=O)N1CCC[C@@H](N)C1, NC(C(O)=O)c1ccccc1

InChI

1S/C8H9NO2/c9-7(8(10)11)6-4-2-1-3-5-6/h1-5,7H,9H2,(H,10,11)

InChI key

ZGUNAGUHMKGQNY-UHFFFAOYSA-N

grade

purum

assay

≥98.0% (NT)

mp

290 °C (subl.) (lit.)

application(s)

peptide synthesis

Storage Class

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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Jian-Lian Chen et al.
Analytica chimica acta, 718, 130-137 (2012-02-07)
Three different approaches for immobilizing cross-linked chitosan molecules (CS-s) in sol-gel phases to form chiral OT-CEC capillaries were comparatively investigated in this study. To synthesize column I, a bare capillary was first silanized with triethoxysilane (TEOS) and then reacted with
Aaron D Mills et al.
Bioorganic & medicinal chemistry letters, 20(1), 87-91 (2009-12-04)
A developing therapy of cystic fibrosis caused by the DeltaF508 mutation in CFTR employs correction of defective CFTR chloride channel gating by a 'potentiator' and of defective CFTR protein folding by a 'corrector'. Based on SAR data for phenylglycine-type potentiators
Motohiro Akazome et al.
The Journal of organic chemistry, 75(3), 660-665 (2010-01-07)
In terms of chiral recognition for racemic aryl methyl sulfoxides in the solid state, three kinds of crystalline (S)-alkylglycyl-(S)-phenylglycines were examined as potential dipeptides host molecules. When (S)-alanyl-(S)-phenylglycines [(S,S)-Ala-Phg] crystallized with aryl methyl sulfoxides, the stereochemistry of preferentially included sulfoxides
Lu Wang et al.
Enzyme and microbial technology, 51(2), 107-112 (2012-06-06)
α-Amino acid ester hydrolases (AEHs) are enzymes of interest to the semi-synthesis of β-lactam antibiotics with α-amino, such as cephalexin and cefaclor. An undesired side reaction, the hydrolysis of α-amino acid ester, had hindered applications in antibiotics synthesis. Although the
José Alixandre de Sousa Luis et al.
Molecules (Basel, Switzerland), 15(1), 128-137 (2010-01-30)
Hydantoins and their derivatives constitute a group of pharmaceutical compounds with anticonvulsant and antiarrhythmic properties, and are also used against diabetes. N-3 and C-5 substituted imidazolidines are examples of such products. As such, we have developed a synthesis of 2,4-dione

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