79850
N-Phthaloylglycine
puriss., ≥99.0% (T)
Synonym(s):
1,3-Dioxo-2-isoindolineacetic acid, Phthalimidoacetic acid
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About This Item
Empirical Formula (Hill Notation):
C10H7NO4
CAS Number:
Molecular Weight:
205.17
UNSPSC Code:
12352200
PubChem Substance ID:
eCl@ss:
32160406
EC Number:
225-177-3
Beilstein/REAXYS Number:
184174
MDL number:
InChI key
WQINSVOOIJDOLJ-UHFFFAOYSA-N
InChI
1S/C10H7NO4/c12-8(13)5-11-9(14)6-3-1-2-4-7(6)10(11)15/h1-4H,5H2,(H,12,13)
SMILES string
OC(=O)CN1C(=O)c2ccccc2C1=O
grade
puriss.
assay
≥99.0% (T)
ign. residue
≤0.05%
application(s)
peptide synthesis
Other Notes
Protected glycine. The acid chloride is employed in (2+2) ketene-imine-cycloadditions
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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C. Hubschwerlen et al.
Organic Syntheses, 72, 14-14 (1995)
Julija Matijević-Sosa et al.
Acta pharmaceutica (Zagreb, Croatia), 58(2), 231-236 (2008-06-03)
The aim of this study was to investigate the activity of N-phthaloyl-glycine-hydroxamic acid (Phth-Gly-HA) as a new iron chelator in vivo to be used in iron overload diseases. After intraperitoneal application of Phth-Gly-HA to male rats (1 mg kg(-1) body
O abu Salach et al.
Pharmaceutical research, 11(10), 1429-1434 (1994-10-01)
Glycine, in addition to GABA, is one of the most important neurotransmitter amino acids. The described structure pharmacokinetic pharmacodynamic relationships (SPPR) study explored the possibility of utilizing phthaloyl derivatives of glycine as new antiepileptics. This was carried out by investigating
Nasima Arshad et al.
Journal of photochemistry and photobiology. B, Biology, 117, 228-239 (2012-11-20)
Ni(II), Cu(II) and Zn(II) metal complexes of N-phthaloylglycine were synthesized, characterized, reported for single crystal X-ray diffraction analysis for Ni(II) complex, and investigated for their binding with DNA under physiological conditions, using spectroscopic (UV-visible and fluorescence) and hydrodynamic techniques. Experimental
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