81275
Poly(ethylene glycol)
tested according to Ph. Eur., 20,000
Synonym(s):
Macrogol 20,000, Polyethylene glycol, Polyoxyethylene, PEG
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About This Item
Linear Formula:
H(OCH2CH2)nOH
CAS Number:
NACRES:
NA.21
PubChem Substance ID:
UNSPSC Code:
12161900
MDL number:
InChI
1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2
InChI key
LYCAIKOWRPUZTN-UHFFFAOYSA-N
agency
tested according to Ph. Eur.
form
flakes
mol wt
16000-24000
greener alternative product characteristics
Safer Solvents and Auxiliaries
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sustainability
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application(s)
pharmaceutical (small molecule)
greener alternative category
Quality Level
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General description
Polyethylene glycol (PEG) is a versatile and non-ionic polymer commonly used in a range of industrial and pharmaceutical applications due to its low toxicity, hydrophobic nature, and semicrystalline structure. It is made up of CH2-CH2O repeating units and its ability to exist in both monomer and aqueous phases at high temperatures makes it valuable for a range of research applications.
We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Green Chemistry. Polyethylene glycol (PEG) is an eco-friendly, biodegradable polymer widely used in pharmaceuticals and cosmetics. Its non-toxic nature and versatility make it a sustainable choice, derived from renewable resources, contributing to greener product formulations. Click here for more information.
Application
- Novel fibrous Ag(NP) decorated clay-polymer composite: Implications in water purification contaminated with predominant micro-pollutants and bacteria: This study demonstrates the use of poly(ethylene glycol) (PEG) for the creation of novel fibrous clay-polymer composites, enhancing the removal efficiency of micro-pollutants and bacteria in water treatment systems (Goswami et al., 2024).
- Striving for Uniformity: A Review on Advances and Challenges To Achieve Uniform Polyethylene Glycol: This review addresses the advances in the uniform production of poly(ethylene glycol) (PEG), critical for its application in drug delivery and pharmaceutical formulations, discussing the material′s solubility, biocompatibility, and stabilization properties (Bento et al., 2024).
- Assessing the structural stability and drug encapsulation efficiency of poly(ethylene glycol)-poly(L-lactic acid) nanoparticles loaded with atorvastatin calcium: The study evaluates the use of PEG in polymeric nanoparticles, focusing on optimizing drug encapsulation efficiency and stability, which is pivotal for effective drug delivery systems (Feng et al., 2024).
- Design and Evaluation of Nanoscale Materials with Programmed Responsivity towards Epigenetic Enzymes: This research explores the role of PEG in designing responsive nanoscale materials aimed at targeting epigenetic enzymes, showcasing PEG′s versatility in enhancing pharmaceutical applications (Ray et al., 2024).
- Membranes composed of poly(lactic acid)/poly(ethylene glycol) and Ora-pro-nóbis (Pereskia aculeata Miller) extract for dressing applications: This article highlights the application of PEG in developing biocompatible and efficient wound dressing materials, combining poly(lactic acid) and natural extracts to enhance healing processes (Mendes et al., 2024).
Biochem/physiol Actions
Polyethylene glycols (PEGs) or macrogols are broadly used as additives in cosmetics and pharmaceuticals. Addition of this hydrophilic polymer blocks and reverses some types of surfactant inactivation in vitro. PEG can be used as a macroinitiator, stabilizer, or dispersant in the field of emulsion polymerization with the help of its derivatives or modifications.
Features and Benefits
- Environment friendly
- Biocompatible
- Unique solvent solution
Storage Class
10 - Combustible liquids
wgk
WGK 1
flash_point_f
281.5 °F - closed cup
flash_point_c
138.6 °C - closed cup
ppe
Eyeshields, Gloves, type N95 (US)
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Polymer nanocomposites for biomedical applications
Rahmani S, et al.
Journal of Separation Science, 175-215 (2022)
Yiming Shi et al.
Langmuir : the ACS journal of surfaces and colloids, 29(9), 3024-3033 (2013-02-26)
Through zeta potential and surface tension measurements and a series of polymerization experiments, the role of poly(ethylene glycol) (PEG) in the process of surfactant-free polymerization of styrene (St)/methyl methacrylate (MMA) has been investigated experimentally. Nanoscale and stable copolymer particles were
Polyethylene glycol/surfactant mixtures improve lung function after HCl and endotoxin lung injuries.
K W Lu et al.
American journal of respiratory and critical care medicine, 164(8 Pt 1), 1531-1536 (2001-11-13)
Addition of nonionic polymers such as polyethylene glycol (PEG) and dextran ameliorates inactivation of Survanta by a variety of substances in vitro. Addition of polymers to Survanta also improves pulmonary function when used to treat rats with lung injury caused
Katharina Wylon et al.
Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology, 12, 67-67 (2016-12-22)
Polyethylene glycols (PEGs) or macrogols are polyether compounds and are widely used as additives in pharmaceuticals, cosmetics, and food. We report on a Caucasian patient experiencing recurrent severe allergic reactions to several drugs. An extensive diagnostic workup including skin prick
I L Konorova et al.
Patologicheskaia fiziologiia i eksperimental'naia terapiia, (4)(4), 7-9 (1991-07-01)
The search for antiaggregatory compounds is undertaken, as a rule, under in vitro conditions which do not reflect the dynamics of the real process. The present work deals with study of the peculiarities of the development of the collagen induced
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