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Merck
CN

81780

Sigma-Aldrich

1,3-Propanediol

puriss., ≥99.0% (GC)

Synonym(s):

1,3-Dihydroxypropane, Trimethylene glycol

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About This Item

Linear Formula:
HO(CH2)3OH
CAS Number:
Molecular Weight:
76.09
Beilstein:
969155
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
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vapor pressure

0.8 mmHg ( 20 °C)
9.8 mmHg ( 100 °C)

grade

puriss.

Assay

≥99.0% (GC)

refractive index

n20/D 1.440 (lit.)
n20/D 1.440

bp

214 °C/760 mmHg (lit.)

mp

−27 °C (lit.)

density

1.053 g/mL at 25 °C (lit.)

SMILES string

OCCCO[H]

InChI

1S/C3H8O2/c4-2-1-3-5/h4-5H,1-3H2

InChI key

YPFDHNVEDLHUCE-UHFFFAOYSA-N

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Ryosuke Kikuchi et al.
Nature medicine, 20(12), 1464-1471 (2014-11-05)
Peripheral artery disease (PAD) generates tissue ischemia through arterial occlusions and insufficient collateral vessel formation. Vascular insufficiency in PAD occurs despite higher circulating levels of vascular endothelial growth factor A (VEGF-A), a key regulator of angiogenesis. Here we show that
H Biebl et al.
Applied microbiology and biotechnology, 52(3), 289-297 (1999-10-26)
1,3-Propanediol (1,3-PD) production by fermentation of glycerol was described in 1881 but little attention was paid to this microbial route for over a century. Glycerol conversion to 1,3-PD can be carried out by Clostridia as well as Enterobacteriaceae. The main
Charles E Nakamura et al.
Current opinion in biotechnology, 14(5), 454-459 (2003-10-29)
Improvements in the biological production of 1,3-propanediol, a key component of an emerging polymer business, have been realized. Utilizing genes from natural strains that produce 1,3-propanediol from glycerol, metabolic engineering has enabled the development of a recombinant strain that utilizes
Stefan Pflügl et al.
Bioresource technology, 119, 133-140 (2012-06-26)
The aim of this study was to evaluate the natural producer Lactobacillus diolivorans as potential production organism of 1,3-propanediol from glycerol. Different cultivation parameters, such as oxygen supply, feeding-strategy, or medium composition have been tested in batch and fed-batch cultivations.
Claudia E Vickers et al.
Biotechnology letters, 34(4), 585-596 (2011-12-14)
Escherichia coli is currently used by many research institutions and companies around the world as a platform organism for the development of bio-based production processes for bulk biochemicals. A given bulk biochemical bioprocess must be economically competitive with current production

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