81780
1,3-Propanediol
puriss., ≥99.0% (GC)
Synonym(s):
1,3-Dihydroxypropane, Trimethylene glycol
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About This Item
Linear Formula:
HO(CH2)3OH
CAS Number:
Molecular Weight:
76.09
EC Number:
207-997-3
UNSPSC Code:
12352100
PubChem Substance ID:
Beilstein/REAXYS Number:
969155
MDL number:
InChI key
YPFDHNVEDLHUCE-UHFFFAOYSA-N
InChI
1S/C3H8O2/c4-2-1-3-5/h4-5H,1-3H2
SMILES string
OCCCO[H]
vapor pressure
0.8 mmHg ( 20 °C), 9.8 mmHg ( 100 °C)
grade
puriss.
assay
≥99.0% (GC)
bp
214 °C/760 mmHg (lit.)
mp
−27 °C (lit.)
density
1.053 g/mL at 25 °C (lit.)
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Storage Class
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves
Regulatory Information
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Sarbjit S Saini et al.
The Journal of investigative dermatology, 135(1), 67-75 (2014-07-22)
ASTERIA I was a 40-week, randomized, double-blind, placebo-controlled study to evaluate the efficacy and safety of subcutaneous omalizumab as add-on therapy for 24 weeks in patients with chronic idiopathic urticaria/spontaneous urticaria (CIU/CSU) who remained symptomatic despite H1 antihistamine treatment at
E Celińska
Biotechnology advances, 28(4), 519-530 (2010-04-07)
The history of 1,3-propanediol (1,3-PD) conversion from being a specialty chemical to being a bulk chemical illustrates that the concerted effort of different metabolic engineering approaches brings the most successful results. In order to metabolically tailor the 1,3-PD production pathway
Yanna Huang et al.
Bioresource technology, 128, 505-512 (2012-12-04)
Fed-batch cultures of Klebsiella pneumoniae expressing Escherichia coli aldH were performed under microaerobic conditions to investigate the effects on metabolites production. Increasing the aeration rate enhanced cell growth and 3-hydroxypropionic acid (3-HP) production, but reduced 1,3-propanediol (1,3-PDO) formation. The recombinant
R K Saxena et al.
Biotechnology advances, 27(6), 895-913 (2009-08-12)
1,3-Propanediol, a valuable bifunctional molecule, can be produced from renewable resources using microorganisms. It has several promising properties for many synthetic reactions, particularly for polymer and cosmetic industries. By virtue of being a natural product, relevant biochemical pathways can be
Ryosuke Kikuchi et al.
Nature medicine, 20(12), 1464-1471 (2014-11-05)
Peripheral artery disease (PAD) generates tissue ischemia through arterial occlusions and insufficient collateral vessel formation. Vascular insufficiency in PAD occurs despite higher circulating levels of vascular endothelial growth factor A (VEGF-A), a key regulator of angiogenesis. Here we show that
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