82282
1,2-Propanediol
purum, ≥98.0% (GC)
Synonym(s):
Propylene glycol
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About This Item
Linear Formula:
CH3CH(OH)CH2OH
CAS Number:
Molecular Weight:
76.09
EC Number:
200-338-0
UNSPSC Code:
12352100
MDL number:
Beilstein/REAXYS Number:
1340498
InChI
1S/C3H8O2/c1-3(5)2-4/h3-5H,2H2,1H3
InChI key
DNIAPMSPPWPWGF-UHFFFAOYSA-N
SMILES string
CC(O)CO
vapor density
2.62 (vs air)
vapor pressure
0.08 mmHg ( 20 °C)
grade
purum
assay
≥98.0% (GC)
autoignition temp.
779 °F
expl. lim.
12.5 %
refractive index
n20/D 1.432 (lit.), n20/D 1.433
mp
−60 °C (lit.)
density
1.036 g/mL at 25 °C (lit.)
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Other Notes
This product has been replaced by 134368-Sigma-Aldrich | 1,2-Propanediol, ReagentPlus®, 99% | CH3CH(OH)CH2OH
Legal Information
ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany
Storage Class
10 - Combustible liquids
wgk
WGK 3
flash_point_f
217.4 °F - closed cup
flash_point_c
103 °C - closed cup
ppe
Eyeshields, Gloves
Regulatory Information
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Glycerol hydrogenolysis to 1, 2-propanediol catalyzed by a heat-resistant ion-exchange resin combined with Ru/C.
Miyazawa T, et al.
Applied Catalysis A: General, 329, 30-35 (2007)
B Lassalle et al.
Fertility and sterility, 44(5), 645-651 (1985-11-01)
Eighty-five human embryos fertilized in vitro were frozen and thawed with 1,2 propanediol as a cryoprotective agent. The effects of viability of in vitro culture duration, stage, and morphologic appearance of embryos were examined after thawing. Survival was higher for
D A Gook et al.
Human reproduction (Oxford, England), 8(7), 1101-1109 (1993-07-01)
Human and mouse oocytes were cryopreserved by a slow freeze, rapid thaw method, using propanediol (PROH) as the cryoprotectant. A simulated cryopreservation was also included in the study to detect the level of damage attributable to the PROH alone. Comparison
Gai Ling Li et al.
Journal of controlled release : official journal of the Controlled Release Society, 84(1-2), 49-57 (2002-10-26)
To achieve a therapeutical effect of the anti-Parkinson's drug R-apomorphine via iontophoresis delivery, enhancement strategies in vitro were explored using three structurally related enhancers, lauric acid (LA), dodecyltrimethylammonium bromide (DTAB) and Laureth-3 oxyethylene ether (C(12)EO(3)). Human stratum corneum and shed
R S Rajasenan et al.
Toxicology and applied pharmacology, 135(1), 89-99 (1995-11-01)
Engrafting components of human immune systems in severe combined immunodeficient (SCID) mice has been utilized to investigate the pathogenesis of several human autoimmune diseases and may provide a model for studying idiosyncratic drug toxicity. The purpose of this investigation was
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