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Merck
CN

82400

Ethylene glycol monopropyl ether

puriss., ≥99.0% (GC)

Synonym(s):

2-Propoxyethanol, Propyl glycol

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About This Item

Linear Formula:
CH3CH2CH2OCH2CH2OH
CAS Number:
2807-30-9
Molecular Weight:
104.15
EC Number:
220-548-6
UNSPSC Code:
12352100
PubChem Substance ID:
24887969
Beilstein/REAXYS Number:
1731983
MDL number:
MFCD00072645

Key Documents

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InChI key

YEYKMVJDLWJFOA-UHFFFAOYSA-N

InChI

1S/C5H12O2/c1-2-4-7-5-3-6/h6H,2-5H2,1H3

SMILES string

CCCOCCO

vapor pressure

1.3 mmHg ( 20 °C)

grade

puriss.

assay

≥99.0% (GC)

bp

150-153 °C (lit.)

mp

−75 °C (lit.)

density

0.913 g/mL at 25 °C (lit.)

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pictograms

FlameExclamation mark
GHS02,GHS07

signalword

Warning

Hazard Classifications

Acute Tox. 4 Dermal - Eye Irrit. 2 - Flam. Liq. 3

Storage Class

3 - Flammable liquids

wgk

WGK 1

flash_point_f

118.4 °F - closed cup

flash_point_c

48 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

Regulatory Information

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R Loch-Caruso et al.
Environmental health perspectives, 57, 119-123 (1984-08-01)
Intercellular communication most likely plays a significant coordinating role in morphogenesis. Blockage of a specific type of intercellular communication, that mediated by gap junctions, has been proposed as a mechanism of action of some teratogens. Several glycol ethers have recently
W J Krasavage et al.
Fundamental and applied toxicology : official journal of the Society of Toxicology, 15(3), 517-527 (1990-10-01)
To determine the potential developmental toxicity of ethylene glycol monopropyl ether (EGPE), groups of pregnant New Zealand white rabbits were exposed to target concentrations of 0, 125, 250, or 500 ppm EGPE vapors for 6 hr a day on Days
W J Krasavage et al.
Teratology, 32(1), 93-102 (1985-08-01)
In order to determine the potential developmental toxicity of ethylene glycol monopropyl ether (EGPE), pregnant rats were exposed to vapor concentrations of 100, 200, 300, or 400 ppm of the compound for 6 hours per day on days 6-15 of
G V Katz et al.
Environmental health perspectives, 57, 165-175 (1984-08-01)
The acute toxicity of ethylene glycol monopropyl ether (EGPE) and ethylene glycol monopropyl ether acetate (EGPEA) was determined in a series of standardized tests. The oral LD50 in rats was 3089 and 9456 mg/kg EGPE and EGPEA, respectively. Skin irritation
Jochem Louisse et al.
Toxicological sciences : an official journal of the Society of Toxicology, 118(2), 470-484 (2010-09-14)
At present, regulatory assessment of systemic toxicity is almost solely carried out using animal models. The European Commission's REACH legislation stimulates the use of animal-free approaches to obtain information on the toxicity of chemicals. In vitro toxicity tests provide in

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