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Merck
CN

83698

Rhodamine 6G

Synonym(s):

Basic Red 1

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About This Item

Linear Formula:
C28H31N2O3Cl
CAS Number:
Molecular Weight:
479.01
EC Number:
213-584-9
PubChem Substance ID:
UNSPSC Code:
12171500
Beilstein/REAXYS Number:
3900071
MDL number:
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InChI

1S/C28H30N2O3.ClH/c1-6-29-23-15-25-21(13-17(23)4)27(19-11-9-10-12-20(19)28(31)32-8-3)22-14-18(5)24(30-7-2)16-26(22)33-25;/h9-16,29H,6-8H2,1-5H3;1H/b30-24+;

InChI key

VYXSBFYARXAAKO-WTKGSRSZSA-N

SMILES string

Cl.CCNc1cc2OC3=CC(=N/CC)\C(C)=CC3=C(c2cc1C)c4ccccc4C(=O)OCC

technique(s)

titration: suitable

suitability

suitable for microscopy

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Biochem/physiol Actions

A rhodamine analog useful in Pgp efflux assays. Has been used to characterize kinetics of MRP1- mediated efflux.

Analysis Note

λmax. ∼524 nm, E(1%/1cm) ∼1700-2000 (Wasser)

signalword

Danger

Hazard Classifications

Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Sens. 1

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

Regulatory Information

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Sarah Tsao et al.
Antimicrobial agents and chemotherapy, 53(4), 1344-1352 (2009-02-19)
Candida albicans frequently develops resistance to treatment with azole drugs due to the acquisition of gain-of-function mutations in the transcription factor Tac1p. Tac1p hyperactivation in azole-resistant isolates results in the constitutive overexpression of several genes, including CDR1 and CDR2, which
Christian Eggeling et al.
Chemphyschem : a European journal of chemical physics and physical chemistry, 6(5), 791-804 (2005-05-11)
Under high-excitation irradiance conditions in one- and two-photon induced fluorescence microscopy, the photostability of fluorescent dyes is of crucial importance for the detection sensitivity of single molecules and for the contrast in fluorescence imaging. Herein, we report on the dependence
Asmahan Abu-Arish et al.
Biophysical journal, 97(8), 2164-2178 (2009-10-22)
The GTPase Ran is a key regulator of molecular transport through nuclear pore complex (NPC) channels. To analyze the role of Ran in its nuclear transport function, we used several quantitative fluorescence techniques to follow the distribution and dynamics of
M Ursula Norman et al.
The American journal of pathology, 172(6), 1638-1649 (2008-05-10)
The role that mast cells play during contact hypersensitivity (CS) response is unclear because some studies have shown that mast cell-deficient mice have relatively intact CS responses whereas others have shown opposing results. Mast cells secrete a wide range of
Ping Wu et al.
Analytical chemistry, 84(18), 7692-7699 (2012-08-29)
The aptamer (S2.2)-guided Ag-Au nanostructures (aptamer-Ag-Au) have been synthesized by photoreduction and validated by ultraviolet-visible light (UV-vis) spectra and transmission electron microscopy (TEM) images. Differential interference contrast (DIC), fluorescence, and TEM images, and surface-enhanced Raman scattering (SERS) spectra indicated that

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