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Merck
CN

85070

Sesamol

purum, ≥98.0% (GC)

Synonym(s):

3,4-(Methylenedioxy)phenol, 5-Benzodioxolol

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About This Item

Empirical Formula (Hill Notation):
C7H6O3
CAS Number:
Molecular Weight:
138.12
EC Number:
208-561-5
UNSPSC Code:
12352100
PubChem Substance ID:
Beilstein/REAXYS Number:
127405
MDL number:
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grade

purum

assay

≥98.0% (GC)

mp

62-65 °C

SMILES string

Oc1ccc2OCOc2c1

InChI

1S/C7H6O3/c8-5-1-2-6-7(3-5)10-4-9-6/h1-3,8H,4H2

InChI key

LUSZGTFNYDARNI-UHFFFAOYSA-N

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pictograms

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signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Lakshmanan Vennila et al.
Archives of pharmacal research, 35(8), 1465-1470 (2012-09-04)
Myocardial infarction is the leading cause of death all over the world. Sesamol is a potent phenolic antioxidant contained only in processed sesame oil and possesses potent chemopreventive, antimutagenic, antihepatotoxic and antioxidation properties. This study was undertaken to investigate the
Vandita Kakkar et al.
Rejuvenation research, 14(6), 597-604 (2011-10-08)
The physicochemical nature of sesamol (logP 1.29; solubility 38.8 mg/mL) substantially enhances its tissue distribution, minimizing its brain delivery. Sesamol-loaded solid lipid nanoparticles (S-SLNs) with an average particle size of 122 nm and an entrapment efficiency of 75.9 ± 2.91% were developed. Biochemical and
Rekha R Shenoy et al.
Journal of ethnopharmacology, 133(2), 608-612 (2010-11-03)
ETHNO-PHARMACOLOGICAL RELEVANCE: The seeds of Sesamum indicum Linn. (Pedaliaceae) has been used traditionally for the treatment of wounds in Buldhana district of Maharashtra state. Sesamol is the main anti-oxidative constituent contained mainly in the processed sesame seed oil which has
K Mishra et al.
Radiation research, 176(5), 613-623 (2011-09-09)
Protection against radiation-induced DNA strand breaks is an important aspect in the design and development of a radioprotector. In this study, the radioprotective efficacy of sesamol, a natural antioxidant, was investigated in aqueous solution of plasmid DNA (pBR322) and compared
C Mahendra Kumar et al.
Biochimie, 93(3), 562-569 (2010-12-15)
Sesamin, sesamolin (lignans) and sesamol--from sesame seed (Sesamum indicum L.)--are known for their health promoting properties. We examined the inhibition effect of sesamol, a phenolic degradation product of sesamolin, on the key enzyme in melanin synthesis, viz. tyrosinase, in vitro.

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