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Merck
CN

85875

Sigma-Aldrich

trans-Stilbene oxide

purum, ≥98.0% (HPLC)

Synonym(s):

trans-1,2-Diphenyloxirane

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About This Item

Empirical Formula (Hill Notation):
C14H12O
CAS Number:
Molecular Weight:
196.24
Beilstein:
82740
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
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grade

purum

Assay

≥98.0% (HPLC)

mp

65-67 °C (lit.)
66-69 °C

SMILES string

O1[C@@H]([C@H]1c2ccccc2)c3ccccc3

InChI

1S/C14H12O/c1-3-7-11(8-4-1)13-14(15-13)12-9-5-2-6-10-12/h1-10,13-14H/t13-,14-/m1/s1

InChI key

ARCJQKUWGAZPFX-ZIAGYGMSSA-N

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Other Notes

This product has been replaced by S4921-ALDRICH | trans-Stilbene oxide 98%

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Vito Capriati et al.
Organic letters, 7(22), 4895-4898 (2005-10-21)
[reaction: see text] A stereoselective/stereospecific synthesis of polysubstituted tetrahydronaphthols based on the Michael addition of ortho-lithiated stilbene oxides to alpha,beta-unsaturated Fischer carbene complexes followed by an unusual cyclization of the corresponding intermediate in a 6-endo-tet mode is described.
Yongping Zhang et al.
Journal of chromatography. A, 1191(1-2), 188-192 (2007-12-07)
A facile strategy based on click chemistry for preparation of the structurally well-defined native beta-cyclodextrin (beta-CD) based chiral stationary phase (CSP) was proposed. The beta-CD CSP was evaluated by enatioseparation of benzoin, trans-stilbene oxide, Troger's base, bendroflumethiazide, ketoprofen, chlorthalidone, three
Ylva Ivarsson et al.
Biochimica et biophysica acta, 1770(9), 1374-1381 (2007-08-11)
Based on the crystal structure of human glutathione transferase M1-1, cysteine residues were introduced in the substrate-binding site of a Cys-free mutant of the enzyme, which were subsequently alkylated with 1-iodoalkanes. By different combinations of site-specific mutations and chemical modifications
B Schilter et al.
The Journal of pharmacology and experimental therapeutics, 294(3), 916-922 (2000-08-17)
Oxidative biotransformation, coupled with genetic variability in enzyme expression, has been the focus of hypotheses interrelating environmental and genetic factors in the etiology of central nervous system disease processes. Chemical modulation of cerebral cytochrome P450 (P450) monooxygenase expression character may
S Bernardini et al.
Mutagenesis, 16(3), 277-281 (2001-04-26)
About 50% and 15% of Caucasians lack the glutathione S-transferase M1 (GSTM1) and T1 (GSTT1) genes and the corresponding enzyme activity, respectively. Both of these polymorphisms have been shown to affect the genotoxicity of some epoxides in cultured human lymphocytes.

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