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Merck
CN

87300

Gly-Gly-Gly-Gly

purum, ≥98.0% (TLC)

Synonym(s):

Glycyl-glycyl-glycyl-glycine, Tetraglycine, Triglycyl-glycine

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About This Item

Linear Formula:
NH2CH2CO(NHCH2CO)3OH
CAS Number:
Molecular Weight:
246.22
EC Number:
211-303-4
UNSPSC Code:
12352200
MDL number:
Beilstein/REAXYS Number:
1715387
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InChI

1S/C8H14N4O5/c9-1-5(13)10-2-6(14)11-3-7(15)12-4-8(16)17/h1-4,9H2,(H,10,13)(H,11,14)(H,12,15)(H,16,17)

InChI key

QMOQBVOBWVNSNO-UHFFFAOYSA-N

SMILES string

NCC(=O)NCC(=O)NCC(=O)NCC(O)=O

grade

purum

assay

≥98.0% (TLC)

Storage Class

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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Gitta Schlosser et al.
European journal of mass spectrometry (Chichester, England), 13(5), 331-337 (2008-01-15)
In this work, copper-binding of the tetraglycine peptide (Gly-Gly-Gly-Gly) was studied by electrospray ionization mass spectrometry. Experiments were performed under alkaline conditions, in the presence of ethanolamine (pH 10.95). We observed that the presence of copper(II) ions induces the aggregation
María V Alipázaga et al.
Dalton transactions (Cambridge, England : 2003), (13)(13), 2036-2040 (2004-07-15)
The synergistic effect of Ni(II) and Co(II) on the sulfite induced autoxidation of Cu(II)/tetraglycine was investigated spectrophotometrically at 25.0 degrees C, pH = 9.0, 1 x 10(-5) mol dm(-3) < or = [S(IV)] < or = 8 x 10(-5) mol
Udo H Verkerk et al.
The journal of physical chemistry. A, 115(24), 6683-6687 (2011-05-21)
Collision-induced dissociations of protonated (18)O-labeled tetraglycines labeled separately at either the first or the second amide bond established that water loss from the backbone occurs from the N-terminal residue. Density functional theory at B3LYP/6-311++G(d,p) predicted that the low-energy [G(4) +
K S Kasprzak et al.
Carcinogenesis, 10(3), 621-624 (1989-03-01)
This study was undertaken to explore whether nuclear chromatin constituents can participate in and/or be affected by redox reactions catalyzed by nickel, like those of nickel complexes with small peptides, e.g. tetraglycine (G4) and oxygen. Calf thymus DNA, nucleohistone (NH)
Takeshi Nagata et al.
The Journal of chemical physics, 134(3), 034110-034110 (2011-01-26)
The gradient for the fragment molecular orbital (FMO) method interfaced with effective fragment potentials (EFP), denoted by FMO∕EFP, was developed and applied to polypeptides solvated in water. The structures of neutral and zwitterionic tetraglycine immersed in water layers of 2.0

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