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Merck
CN

87362

Tetrahydrofuran

≥99.5% (GC)

Synonym(s):

Butylene oxide, Oxolane, Tetramethylene oxide

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About This Item

Empirical Formula (Hill Notation):
C4H8O
CAS Number:
109-99-9
Molecular Weight:
72.11
EC Number:
203-726-8
UNSPSC Code:
12352005
PubChem Substance ID:
329769578
Beilstein/REAXYS Number:
102391
MDL number:
MFCD00005356

Key Documents

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vapor density

2.5 (vs air)

vapor pressure

114 mmHg ( 15 °C), 143 mmHg ( 20 °C)

assay

≥99.5% (GC)

autoignition temp.

610 °F

expl. lim.

1.8-11.8 %

refractive index

n20/D 1.407

bp

65-67 °C (lit.)

mp

−108 °C (lit.)

solubility

H2O: soluble

density

0.889 g/mL at 25 °C (lit.)

λ

1 cm path, H2O reference

UV absorption

λ: 240 nm Amax: 0.3, λ: 250 nm Amax: 0.2, λ: 260 nm Amax: 0.1, λ: 280 nm Amax: 0.03, λ: 310 nm Amax: 0.003

suitability

in accordance for luminescence, suitable for luminescence

SMILES string

C1CCOC1

InChI

1S/C4H8O/c1-2-4-5-3-1/h1-4H2

InChI key

WYURNTSHIVDZCO-UHFFFAOYSA-N

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Todd J Harris et al.
Biomaterials, 31(5), 998-1006 (2009-10-24)
The use of biomaterials for gene delivery can potentially avoid many of the safety concerns with viral gene delivery. However, the efficacy of polymeric gene delivery methods is low, particularly in vivo. One significant concern is that the interior and
Synthetic routes to tetrahydrofuran, tetrahydropyran, and spiroketal units of polyether antibiotics and a survey of spiroketals of other natural products.
Boivin TLB.
Tetrahedron, 43(15), 3309-3362 (1987)
Eagleson M.
Concise Encyclopedia Chemistry, 883-883 (1994)
Eagleson M.
Concise Encyclopedia Chemistry, 152-152 (1994)
Haiying Yu et al.
Biomaterials, 30(4), 508-517 (2008-11-01)
Natural bone growth greatly depends on the precedent vascular network that supplies oxygen and essential nutrients and removes metabolites. Likewise, it is crucial for tissue-engineered bone to establish a vascular network that temporally precedes new bone formation, and spatially originates
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