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Merck
CN

87720

Sigma-Aldrich

Tetramethylammonium chloride

purum, ≥98.0% (AT)

Synonym(s):

TMA

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About This Item

Linear Formula:
(CH3)4N(Cl)
CAS Number:
Molecular Weight:
109.60
Beilstein:
3911201
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
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grade

purum

Assay

≥98.0% (AT)

impurities

≤2% water

mp

>300 °C (lit.)

SMILES string

[Cl-].C[N+](C)(C)C

InChI

1S/C4H12N.ClH/c1-5(2,3)4;/h1-4H3;1H/q+1;/p-1

InChI key

OKIZCWYLBDKLSU-UHFFFAOYSA-M

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Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 2 Oral - Acute Tox. 3 Dermal - Aquatic Chronic 2 - Skin Irrit. 2 - STOT SE 1 Oral

Target Organs

Central nervous system

Storage Class Code

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 1

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Proton NMR and piezoelectricity in tetramethylammonium chloride.
Gibson AAV and Raab RE.
J. Chem. Phys. , 57(11), 4688-4693 (1972)
Low concentrations of tetramethylammonium chloride increase yield and specificity of PCR.
Chevet E, et al.
Nucleic Acids Research, 23(16), 3343-3343 (1995)
Markus Welcker et al.
Genes & development, 27(23), 2531-2536 (2013-12-04)
The Fbw7 tumor suppressor targets a broad network of proteins for ubiquitylation. Here we show critical functions for Fbw7 dimerization in regulating the specificity and robustness of degradation. Dimerization enables Fbw7 to target substrates through concerted binding to two suboptimal
Wei Shen et al.
Chemical communications (Cambridge, England), 49(73), 8114-8116 (2013-08-08)
A simple and low-cost colorimetric assay utilizing ferrofluidic nanoparticulate probes (FNPs) and a ligase for single-nucleotide polymorphism genotyping is described. Excellent sensitivity and selectivity were accomplished through the engagement of the FNPs and a ligase chain reaction.
Marco I Ries et al.
The Journal of biological chemistry, 288(52), 37289-37295 (2013-11-15)
Metabolic profiling and structural elucidation of novel secondary metabolites obtained from derived deletion strains of the filamentous fungus Penicillium chrysogenum were used to reassign various previously ascribed synthetase genes of the roquefortine/meleagrin pathway to their corresponding products. Next to the

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