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Merck
CN

87720

Tetramethylammonium chloride

purum, ≥98.0% (AT)

Synonym(s):

TMA

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About This Item

Linear Formula:
(CH3)4N(Cl)
CAS Number:
75-57-0
Molecular Weight:
109.60
EC Number:
200-880-8
UNSPSC Code:
12352100
PubChem Substance ID:
329769601
Beilstein/REAXYS Number:
3911201
MDL number:
MFCD00011628

Key Documents

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InChI key

OKIZCWYLBDKLSU-UHFFFAOYSA-M

InChI

1S/C4H12N.ClH/c1-5(2,3)4;/h1-4H3;1H/q+1;/p-1

SMILES string

[Cl-].C[N+](C)(C)C

grade

purum

assay

≥98.0% (AT)

impurities

≤2% water

mp

>300 °C (lit.)

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signalword

Danger

Hazard Classifications

Acute Tox. 2 Oral - Acute Tox. 3 Dermal - Aquatic Chronic 2 - Skin Irrit. 2 - STOT SE 1 Oral

target_organs

Central nervous system

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 1

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

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Certificates of Analysis (COA)

Lot/Batch Number
BCBV0084
BCBR8642V
BCBR8636V
BCBR8643V
BCBR8640V

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Low concentrations of tetramethylammonium chloride increase yield and specificity of PCR.
Chevet E, et al.
Nucleic Acids Research, 23(16), 3343-3343 (1995)
Proton NMR and piezoelectricity in tetramethylammonium chloride.
Gibson AAV and Raab RE.
J. Chem. Phys. , 57(11), 4688-4693 (1972)
Markus Welcker et al.
Genes & development, 27(23), 2531-2536 (2013-12-04)
The Fbw7 tumor suppressor targets a broad network of proteins for ubiquitylation. Here we show critical functions for Fbw7 dimerization in regulating the specificity and robustness of degradation. Dimerization enables Fbw7 to target substrates through concerted binding to two suboptimal
Wei Shen et al.
Chemical communications (Cambridge, England), 49(73), 8114-8116 (2013-08-08)
A simple and low-cost colorimetric assay utilizing ferrofluidic nanoparticulate probes (FNPs) and a ligase for single-nucleotide polymorphism genotyping is described. Excellent sensitivity and selectivity were accomplished through the engagement of the FNPs and a ligase chain reaction.
Marco I Ries et al.
The Journal of biological chemistry, 288(52), 37289-37295 (2013-11-15)
Metabolic profiling and structural elucidation of novel secondary metabolites obtained from derived deletion strains of the filamentous fungus Penicillium chrysogenum were used to reassign various previously ascribed synthetase genes of the roquefortine/meleagrin pathway to their corresponding products. Next to the
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