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Merck
CN

87729

Sigma-Aldrich

Tetramethylammonium hydroxide solution

~25% in H2O

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About This Item

Linear Formula:
(CH3)4N(OH)
CAS Number:
75-59-2
Molecular Weight:
91.15
Beilstein:
3558708
MDL number:
MFCD00008280
UNSPSC Code:
12352100
PubChem Substance ID:
329769603

Key Documents

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concentration

~25% in H2O

impurities

≤0.1% halides (as chloride)

refractive index

n20/D 1.382

anion traces

sulfate (SO42-): ≤1000 mg/kg

SMILES string

[OH-].C[N+](C)(C)C

InChI

1S/C4H12N.H2O/c1-5(2,3)4;/h1-4H3;1H2/q+1;/p-1

InChI key

WGTYBPLFGIVFAS-UHFFFAOYSA-M

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Signal Word

Danger

Hazard Classifications

Acute Tox. 1 Dermal - Acute Tox. 2 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Corr. 1 - STOT RE 1 Dermal - STOT SE 1

Target Organs

Central nervous system, Liver,thymus

Storage Class Code

6.1B - Non-combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Atomic absorption determination of zinc, copper, cadmium, and lead in tissues solubilized by aqueous tetramethylammonium hydroxide.
L Murthy et al.
Analytical biochemistry, 53(2), 365-372 (1973-06-01)
Determination of trace elements in biological materials by ETV-ICP-MS after dissolution or slurry formation with tetramethylammonium hydroxide.
Pozebon D, et al.
Journal of Analytical Atomic Spectrometry, 13(10), 1101-1105 (1998)
Synthesis of Pure Tetramethylammonium Hydroxide Solution Free from Chloride Ion by the Electrolysis of Its Hydrogen Carbonate.
Yagi O and Shimizu S.
Chemistry Letters (Jpn), 12, 2041-2044 (1993)
Validation of an optimized method for the determination of iodine in human breast milk by inductively coupled plasma mass spectrometry (ICPMS) after tetramethylammonium hydroxide extraction.
Huynh D, et al.
Journal of Trace Elements in Medicine and Biology, 29, 75-82 (2015)
Lulu Xie et al.
Science (New York, N.Y.), 342(6156), 373-377 (2013-10-19)
The conservation of sleep across all animal species suggests that sleep serves a vital function. We here report that sleep has a critical function in ensuring metabolic homeostasis. Using real-time assessments of tetramethylammonium diffusion and two-photon imaging in live mice
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