87919
Tetramethylrhodamine methyl ester perchlorate
≥95% (HPCE)
Synonym(s):
TMRM
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About This Item
Linear Formula:
C25H25N2O3 · ClO4
CAS Number:
Molecular Weight:
500.93
PubChem Substance ID:
UNSPSC Code:
12171500
Beilstein/REAXYS Number:
7162165
MDL number:
SMILES string
[O-]Cl(=O)(=O)=O.COC(=O)c1ccccc1C2=C3C=C\C(C=C3Oc4cc(ccc24)N(C)C)=[N+](\C)C
InChI
1S/C25H25N2O3.ClHO4/c1-26(2)16-10-12-20-22(14-16)30-23-15-17(27(3)4)11-13-21(23)24(20)18-8-6-7-9-19(18)25(28)29-5;2-1(3,4)5/h6-15H,1-5H3;(H,2,3,4,5)/q+1;/p-1
InChI key
PFYWPQMAWCYNGW-UHFFFAOYSA-M
assay
≥95% (HPCE)
solubility
DMSO: soluble, alcohols: soluble
fluorescence
λex 540 nm; λem 595 nm in DMSO
suitability
suitable for fluorescence
storage temp.
2-8°C
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
Other Notes
Potential-sensitive probe for measuring membrane potential changes in mitochondria
Regulatory Information
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D L Farkas et al.
Biophysical journal, 56(6), 1053-1069 (1989-12-01)
The distribution of charged membrane-permeable molecular probes between intracellular organelles, the cytoplasm, and the outside medium is governed by the relative membrane electrical potentials of these regions through coupled equilibria described by the Nernst equation. A series of highly fluorescent
Timothy M Tucey et al.
Cell metabolism, 27(5), 988-1006 (2018-05-03)
To fight infections, macrophages undergo a metabolic shift whereby increased glycolysis fuels antimicrobial inflammation and killing of pathogens. Here we demonstrate that the pathogen Candida albicans turns this metabolic reprogramming into an Achilles' heel for macrophages. During Candida-macrophage interactions intertwined
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