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Merck
CN

88481

2-Thiobarbituric acid

purum, ≥98.0% (S)

Synonym(s):

4,6-Dihydroxy-2-mercaptopyrimidine, 4,6-Dihydroxypyrimidine-2-thiol, TBA

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About This Item

Empirical Formula (Hill Notation):
C4H4N2O2S
CAS Number:
Molecular Weight:
144.15
EC Number:
207-985-8
UNSPSC Code:
12352200
PubChem Substance ID:
Beilstein/REAXYS Number:
120663
MDL number:
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grade

purum

assay

≥98.0% (S)

drug control

regulated under CDSA - not available from Sigma-Aldrich Canada

ign. residue

≤0.1%

mp

245 °C (dec.) (lit.)

SMILES string

O=C1CC(=O)NC(=S)N1

InChI

1S/C4H4N2O2S/c7-2-1-3(8)6-4(9)5-2/h1H2,(H2,5,6,7,8,9)

InChI key

RVBUGGBMJDPOST-UHFFFAOYSA-N

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Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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Ezequiel M Salido et al.
Journal of pineal research, 54(2), 179-189 (2012-09-06)
Diabetic retinopathy (DR) is a leading cause of acquired blindness in adults, mostly affected by type 2 diabetes mellitus (T2DM). We have developed an experimental model of early T2DM in adult rats which mimics some features of human T2DM at
Leticia R Benetti et al.
European journal of pharmacology, 698(1-3), 463-469 (2012-11-28)
Recent studies show that endogenous hydrogen sulfide (H(2)S) plays an anti-inflammatory role in the pathogenesis of airway inflammation. This study investigated whether exogenous H(2)S may counteract oxidative stress-mediated lung damage in allergic mice. Female BALB/c mice previously sensitized with ovalbumin
Sechang Oh et al.
Hepatology (Baltimore, Md.), 61(4), 1205-1215 (2014-10-02)
Recently, the beneficial effects of increased physical activity (PA) on nonalcoholic fatty liver disease (NAFLD) in obese subjects were reported. However, the optimal strength and volume of PA in lifestyle modification to improve NAFLD pathophysiology and be recommended as an
Ismael Galván et al.
Physiological and biochemical zoology : PBZ, 85(4), 332-347 (2012-06-19)
The synthesis of melanins, which are the most common animal pigments, is influenced by glutathione (GSH), a key intracellular antioxidant. At high GSH levels, pheomelanin (the lightest melanin form) is produced, whereas production of eumelanin (the darkest melanin form) does
Antonios Papastergiadis et al.
Journal of agricultural and food chemistry, 60(38), 9589-9594 (2012-09-07)
The ability of the spectrophotometric thiobarbituric acid reactive substances (TBARS) test to determine malondialdehyde (MDA) in various food matrices was evaluated. MDA was extracted from the foods; the extract reacted with thiobarbituric acid (TBA); and the formed TBA-MDA adduct was

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