Key Documents

View All Documentation

89050

Thiosemicarbazide

Name: Thiosemicarbazide
Brand: SIAL

puriss. p.a., 98%

Synonym(s):

Thiocarbamoyl hydrazide

Select a Size

Change View

About This Item

Linear Formula:

NH₂CSNHNH₂

CAS Number:

79-19-6

Molecular Weight:

91.14

UNSPSC Code:

12352100

NACRES:

NA.22

PubChem Substance ID:

329769689

EC Number:

201-184-7

Beilstein/REAXYS Number:

506320

MDL number:

MFCD00007620

Assay:

98%

Form:

crystals

Technical Service

Need help? Our team of experienced scientists is here for you.

Let Us Assist

grade

puriss. p.a.

Quality Level

100

assay

98%

form

crystals

ign. residue

≤0.08% (as SO₄)

mp

180-183 °C (dec.) (lit.)

anion traces

sulfate (SO₄^2-): ≤100 mg/kg

cation traces

Ca: ≤50 mg/kg, Cd: ≤5 mg/kg, Co: ≤5 mg/kg, Cr: ≤5 mg/kg, Cu: ≤5 mg/kg, K: ≤50 mg/kg, Mg: ≤5 mg/kg, Mn: ≤5 mg/kg, Na: ≤50 mg/kg, Ni: ≤5 mg/kg, Pb: ≤5 mg/kg, Zn: ≤5 mg/kg

functional group

amine, hydrazine, thiourea

SMILES string

NNC(N)=S

InChI

1S/CH5N3S/c2-1(5)4-3/h3H2,(H3,2,4,5)

InChI key

BRWIZMBXBAOCCF-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

General description

Thiosemicarbazide is an environmentally toxic compound, which is usually derived from thiourea. Its ability to chelate trace metals promotes its biological activity against certain tumors, protozoa, influenza, pesticides, and fungicides. It is widely used as a metal complexing agent in various fields involving the characterization of aliphatic or aromatic aldehydes, ketones, and polysaccharides.

Application

Thiosemicarbazide has been used as an analytical reagent for the measurement of urea net high-affinity uptake in roots of intact maize plants using colorimetric assay.

pictograms

GHS06

signalword

Danger

hcodes

H300,H412

pcodes

P264 - P270 - P273 - P301 + P310 - P405 - P501

Hazard Classifications

Acute Tox. 2 Oral - Aquatic Chronic 3

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

Regulatory Information

农药列管产品

This item has

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Electrochemical determination of thiosemicarbazide using the glassy carbon electrode modified with multi-walled carbon nanotubes

Faizbakhsh N and Safari Z

Advances in Nanochemistry, 1(2), 52-55 (2019)

Measurement of net high-affinity urea uptake in maize plants

Zanin L, et al.

Bio-protocol, 5 (2015)

Antifungal effect of 4-arylthiosemicarbazides against Candida species. Search for molecular basis of antifungal activity of thiosemicarbazide derivatives.

Agata Siwek et al.

Journal of molecular modeling, 18(9), 4159-4170 (2012-04-27)

The in vitro antifungal potency of six series of 4-arylthiosemicarbazides was evaluated. Two isoquinoline derivatives with an ortho-methoxy or ortho-methyl group at the phenyl ring were the most potent antifungal agents. Molecular modeling studies and docking of all 4-arylthiosemicarbazides into

Synthesis, crystal structures, and biological evaluation of manganese(II) and nickel(II) complexes of 4-cyclohexyl-1-(1-(pyrazin-2-yl)ethylidene)thiosemicarbazide.

Ming Xue Li et al.

European journal of medicinal chemistry, 46(9), 4383-4390 (2011-07-26)

4-Cyclohexyl-1-(1-(pyrazin-2-yl)ethylidene)thiosemicarbazide (HL) and its transition metal complexes formulated as [Mn(L)(2)] (1) and [Ni(L)(2)] (2) have been prepared in 55-75% yield and characterized by elemental analysis, IR, MS, NMR and single-crystal X-ray diffraction studies. Biological activities of the synthesized compounds have

Synthesis and antitumor activity of novel quinazoline derivatives containing thiosemicarbazide moiety.

Junbo He et al.

European journal of medicinal chemistry, 54, 925-930 (2012-07-04)

Series of novel derivatives of quinazoline containing thiosemicarbazide moiety 5 and 9 have been synthesized and tested for their antitumor activities in vitro against a panel of five human cancer cell lines. Bioassay results indicated that most of the prepared

View All Related Papers

Global Trade Item Number

SKU	GTIN
89050-100G	04061833065488
89050-25G	04061833065495

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service