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Merck
CN

89061

Eriodictyol

analytical standard

Synonym(s):

3·,4·,5,7-Tetrahydroxyflavanone

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About This Item

Empirical Formula (Hill Notation):
C15H12O6
CAS Number:
Molecular Weight:
288.25
PubChem Substance ID:
UNSPSC Code:
85151701
NACRES:
NA.24
EC Number:
209-016-4
MDL number:
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InChI key

SBHXYTNGIZCORC-CYBMUJFWSA-N

InChI

1S/C15H12O6/c16-8-4-11(19)15-12(20)6-13(21-14(15)5-8)7-1-2-9(17)10(18)3-7/h1-5,13,16-19H,6H2/t13-/m1/s1

grade

analytical standard

assay

≥98.0% (HPLC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

impurities

≤5.0% water

application(s)

food and beverages

format

neat

Quality Level

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General description

Eriodictyol is a naturally occurring flavonoid found in citrus fruits. It can be isolated from the chinese herb, Dracocephalum rupestre. It may possess antioxidant activity.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Other Notes

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
For this product we use the non-stereospecific CAS number. It is expected that the natural enantiomer is predominant, however the substance is prone to racemization in solution. The product is therefore not specified stereospecifically and is only recommended to be used for non-stereospecific analysis.
This compound is commonly found in plants of the genus: mentha silybum thymus

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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The flavonoid, eriodictyol, induces long-term protection in ARPE-19 cells through its effects on Nrf2 activation and phase 2 gene expression
Johnson J, et al.
Investigative Ophthalmology & Visual Science, 50, 2398-2406 (2009)
B A 'T Hart et al.
Chemico-biological interactions, 73(2-3), 323-335 (1990-01-01)
The mechanism by which (a panel of) flanonoids inhibit the production of luminol-dependent chemiluminescence (CLlum) by activated human neutrophils is subject to this study. CLlum is frequently used as a bio-assay to quantify the effect of xenobiotics on the production
S Ogata et al.
Bioscience, biotechnology, and biochemistry, 64(5), 1075-1078 (2000-07-06)
The flavonoid from lemon fruit (Citrus limon BURM. f.) and its metabolites, particularly eriodictyol, 3,4-dihydroxyhydrocinnamic acid, and phloroglucinol had the function of DNA fragmentation in HL-60 cells when analyzed by flow cytometry. An apoptotic DNA ladder and chromatin condensation were
C Huang et al.
Xenobiotica; the fate of foreign compounds in biological systems, 39(4), 312-322 (2009-04-08)
Dietary flavonoids catechin, epicatechin, eriodictyol, and hesperetin were investigated as substrates and inhibitors of human sulfotransferases (hSULTs). Purified recombinant proteins and human intestine cytosol were used as enzyme sources. hSULT1A1 and hSULT1A3 as well as human intestine cytosol can catalyse
Eung-Ryoung Lee et al.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 27(5), 513-524 (2011-06-22)
Although flavonoids exhibit a variety of beneficial biological activities, the exact molecular mechanism of the cellular effects is still not fully explained. In this study, we investigated the molecular mechanism of cytoprotective effect of eriodictyol in UV-irradiated keratinocytes. We found

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