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89464

2-[N-(7-Nitro-4-benzofurazanyl)methylamino]acethydrazide

Name: 2-[<I>N</I>-(7-Nitro-4-benzofurazanyl)methylamino]acethydrazide
Brand: SIAL

suitable for fluorescence, ≥97.0% (CHN)

Synonym(s):

4-(N-Hydrazinocarbonylmethyl-N-methylamino)-7-nitro-benzofurazan, N-(7-Nitro-4-benzofurazanyl]sarcosinehydrazide, DBD-CO-Hz

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About This Item

Empirical Formula (Hill Notation):

C₉H₁₀N₆O₄

CAS Number:

221263-97-4

Molecular Weight:

266.21

NACRES:

NA.22

PubChem Substance ID:

329769741

UNSPSC Code:

41115710

MDL number:

MFCD02093433

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Quality Level

100

assay

≥97.0% (CHN)

form

powder

fluorescence

λ_ex 483 nm; λ_em 533 nm in acetonitrile

suitability

suitable for fluorescence

storage temp.

2-8°C

SMILES string

CN(CC(=O)NN)c1ccc([N+]([O-])=O)c2nonc12

InChI

1S/C9H10N6O4/c1-14(4-7(16)11-10)5-2-3-6(15(17)18)9-8(5)12-19-13-9/h2-3H,4,10H2,1H3,(H,11,16)

InChI key

IDJGYEQXPMQJKF-UHFFFAOYSA-N

General description

Fluorescence of an analyte, whether natural or induced by derivatization using chemicals such as 2-[N-(7-nitro-4-benzofurazanyl)methylamino]acethydrazide, can be leveraged to increase the sensitivity (detect lower levels) of the analysis. In addition, the uniqueness of fluorescent character can allow for the selective identification of a molecule in a complex mixture. Fluorescence is quantifiable at lower concentrations and usually has a wider linear range of response vs. concentration compared to optical (UV-VIS) absorbance.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Other Notes

Derivatizing agent for fluorescence detection of carbonyl compounds with HPLC

Discover LiChropur reagents ideal for HPLC or LC-MS analysis

pictograms

GHS07

signalword

Warning

hcodes

H315,H319,H335

pcodes

P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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N-(4-nitro-2,1,3-benzoxadiazoyl-7-yl)-N-methyl-2-aminoacetohydrazide (NBD-CO-Hz) as a precolumn fluorescent derivatization reagent for carboxylic acids in high-performance liquid chromatography.

T Santa et al.

Journal of pharmaceutical and biomedical analysis, 17(6-7), 1065-1070 (1999-01-12)

A new fluorescent reagent for carboxylic acids, N-(4-nitro-2,1,3-benzoxadiazoyl-7-yl)-N-methyl-2-aminoacetohydr azide (NBD-CO-Hz) was synthesized and its applicability as a precolumn derivatization reagent in high-performance liquid chromatography was examined. NBD-CO-Hz reacted with 2-arylpropionic acids (2-APAs), a group of non-steroidal antiinflammatory drugs (NSAIDs) in

Global Trade Item Number

SKU	GTIN
400091-50MG	04055977212389

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