89749
p-Toluenesulfonamide
purum, ≥99.0% (TLC)
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About This Item
Linear Formula:
CH3C6H4SO2NH2
CAS Number:
Molecular Weight:
171.22
EC Number:
200-741-1
UNSPSC Code:
12352100
PubChem Substance ID:
Beilstein/REAXYS Number:
472689
MDL number:
InChI key
LMYRWZFENFIFIT-UHFFFAOYSA-N
InChI
1S/C7H9NO2S/c1-6-2-4-7(5-3-6)11(8,9)10/h2-5H,1H3,(H2,8,9,10)
SMILES string
Cc1ccc(cc1)S(N)(=O)=O
grade
purum
assay
≥99.0% (TLC)
Gene Information
human ... CA1(759), CA2(760), CA5A(763), CA5B(11238)
mp
135-137 °C
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Storage Class
11 - Combustible Solids
wgk
WGK 1
flash_point_f
395.6 °F - closed cup
flash_point_c
202 °C - closed cup
ppe
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
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A M van Haperen et al.
FEMS microbiology letters, 204(2), 299-304 (2001-12-04)
A bacterium capable of utilising p-toluenesulphonamide was isolated from activated sludge. The isolated strain designated PTSA was identified as a Pseudomonas sp. using chemotaxonomic and genetic studies. Pseudomonas PTSA grew on p-toluenesulphonamide in a chemostat with approximately 90% release of
G Luo et al.
Preparative biochemistry & biotechnology, 38(3), 265-270 (2008-06-24)
A series of 14-alkyl and aryl-14H-dibenzo[a.j]xanthenes have been synthesized with high yields through a one-pot condensation of beta-naphthol with alkyl or aryl aldehydes in the presence of BSA or o-TSA in a solvent-free medium.
Hidehiko Fujisawa et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 12(19), 5082-5093 (2006-04-22)
Lewis base catalyzed Mannich-type reaction between trimethylsilyl enol ethers and N-tosylaldimines is described. Nitrogen anions generated from amides or imides such as lithium benzamide or potassium phthalimide are found to be effective Lewis base catalysts in DMF at room temperature
J Q Zhou et al.
Die Pharmazie, 61(10), 869-873 (2006-10-31)
Aim of this study was to investigate liver metabolism of with regard to para toluene-sulfonamide (PTS), CYP isoforms, P-glycoprotein (P-gp), and drug interactions. Known substrates, inducers and inhibitors of CYP and inhibitor of P-gp were employed and metabolites were determined
Jianxing He et al.
Anti-cancer drugs, 20(9), 838-844 (2009-08-12)
Para-toluenesulfonamide (PTS), active ingredient being PTS, is a new anticancer drug applied through local intratumoral injection. The aim of this phase II clinical trial was to investigate the response and toxicity of standard gemcitabine (GEM) plus cisplatin (CIS) chemotherapy with
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