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Merck
CN

90187

Sigma-Aldrich

T-2 Toxin

≥98.0% (TLC)

Synonym(s):

12,13-Epoxytrichothec-9-ene-3,4,8,15-tetrol-4,15-diacetate-8-isovalerate, 4β,15-Diacetoxy-3α-hydroxy-8α-(3-methylbutyryloxy)-12,13-epoxytrichothec-9-ene

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About This Item

Empirical Formula (Hill Notation):
C24H34O9
CAS Number:
21259-20-1
Molecular Weight:
466.52
Beilstein:
3575695
EC Number:
244-297-7
MDL number:
MFCD00871255
UNSPSC Code:
12352200
PubChem Substance ID:
329769858

Key Documents

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Assay

≥98.0% (TLC)

form

powder

SMILES string

[H][C@]12O[C@]3([H])[C@H](O)[C@@H](OC(C)=O)[C@](C)([C@@]1(COC(C)=O)C[C@H](OC(=O)CC(C)C)C(C)=C2)[C@]34CO4

InChI

1S/C24H34O9/c1-12(2)7-18(27)32-16-9-23(10-29-14(4)25)17(8-13(16)3)33-21-19(28)20(31-15(5)26)22(23,6)24(21)11-30-24/h8,12,16-17,19-21,28H,7,9-11H2,1-6H3/t16-,17+,19+,20+,21+,22+,23+,24-/m0/s1

InChI key

BXFOFFBJRFZBQZ-QYWOHJEZSA-N

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Other Notes

Reference in the quantitative determination of trichothecenes

Disclaimer

mycotoxin; severe poison

Pictograms

Skull and crossbones
GHS06

Signal Word

Danger

Hazard Statements

H300 + H310 + H330,H315

Hazard Classifications

Acute Tox. 1 Dermal - Acute Tox. 1 Inhalation - Acute Tox. 1 Oral - Skin Irrit. 2

Storage Class Code

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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High-performance liquid chromatography of trichothecenes. I. Detection of T-2 toxin and HT-2 toxin.
R Schmidt et al.
Journal of chromatography, 212(3), 370-373 (1981-08-07)
Fresenius Journal of Analytical Chemistry, 317, 665-665 (1984)
R. Schmidt et al.
Zeitschrift fur Lebensmittel-Untersuchung Und -Forschung, 175, 169-169 (1982)
A Osselaere et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 55, 150-155 (2013-01-15)
The effects of the mycotoxin T-2 on hepatic and intestinal drug-metabolizing enzymes (cytochrome P450) and drug transporter systems (MDR1 and MRP2) in poultry were investigated during this study. Broiler chickens received either uncontaminated feed, feed contaminated with 68μg/kg or 752μg/kg
Susan P McCormick et al.
Applied and environmental microbiology, 78(24), 8694-8702 (2012-10-09)
Trichothecenes are sesquiterpenoid toxins produced by Fusarium species. Since these mycotoxins are very stable, there is interest in microbial transformations that can remove toxins from contaminated grain or cereal products. Twenty-three yeast species assigned to the Trichomonascus clade (Saccharomycotina, Ascomycota)
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