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901989

Tetrazine-NHS ester

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About This Item

Empirical Formula (Hill Notation):
C14H11N5O4
Molecular Weight:
313.27
UNSPSC Code:
12352200
NACRES:
NA.22
MDL number:
MFCD29052194
Form:
powder
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form

powder

availability

available only in USA

mp

171-177 °C

storage temp.

−20°C

Application

Tetrazine-NHS ester demonstrates exceptionally fast cycloaddition kinetics with trans-cyclooctene (TCO) as the dienophile (up to 30,000 M-1 s-1). These have been the fastest kinetics reported for a bioorthogonal reaction. The chemical stability of tetrazines is substantially lower compared to methyltetrazines, thus requiring more careful selection of reagents and conditions for chemical transformation. However, tetrazine chemistry is still in an acceptable range for many applications.

pictograms

Flame
GHS02

signalword

Danger

hcodes

H242

Hazard Classifications

Self-react. C

Storage Class

5.2 - Organic peroxides and self-reacting hazardous materials

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
MKCM4356

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Global Trade Item Number

SKUGTIN
901989-25MG04061838635150