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Merck
CN

91214

Isofraxidin

analytical standard

Synonym(s):

6,8-Dimethoxyumbelliferone, 7-Hydroxy-6,8-dimethoxychromen-2-one, 7-Hydroxy-6,8-dimethoxycoumarin

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About This Item

Empirical Formula (Hill Notation):
C11H10O5
CAS Number:
Molecular Weight:
222.19
UNSPSC Code:
85151701
NACRES:
NA.24
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
202652
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grade

analytical standard

Quality Level

assay

≥98.0% (HPLC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

impurities

≤5.0% water

application(s)

food and beverages

format

neat

storage temp.

2-8°C

SMILES string

COc1cc2C=CC(=O)Oc2c(OC)c1O

InChI

1S/C11H10O5/c1-14-7-5-6-3-4-8(12)16-10(6)11(15-2)9(7)13/h3-5,13H,1-2H3

InChI key

HOEVRHHMDJKUMZ-UHFFFAOYSA-N

General description

Isofraxidin is a major active constituent, isolated from Sarcandra glabra plant with a variety of biological properties such as antifatigue, antistress, anticancer, immunoaccomondating and cholagogic effects.

Application

Isofraxidin may be used as an analytical reference standard for the separartion and quantification of the analyte in Sarcandra glabra plant and Acanthopanax senticosus Harms using different chromatography techniques.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.


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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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J H Kwak et al.
Journal of natural products, 64(8), 1081-1083 (2001-08-25)
Four new coumarin monoterpene ethers, artekeiskeanols A-D (1-4), and three known coumarins, isofraxidin, fraxidin, and daphnoretin, were isolated from the whole plants of Artemisia keiskeana. All structures were determined from spectral data, and that of artekeiskeanol A (1) was confirmed
Xiaofeng Niu et al.
International immunopharmacology, 14(2), 164-171 (2012-07-18)
Isofraxidin (IF) is a Coumarin compound that can be isolated from medicinal plants, such as Sarcandra glabra (Thunb.). Nakai is widely used in Asian countries for the treatment of anti-bacterial, anti-inflammatory and anti-tumour action. The present investigation was designed to
Jiaqin Liu et al.
Biopolymers, 73(4), 443-450 (2004-03-03)
The binding of isofraxidin to bovine serum albumin (BSA) was studied under physiological conditions with BSA concentration of 1.5 x 10(-6) mol x L(-1) and drug concentration in the range of 1.67 x 10(-6) mol x L(-1) to 2.0 x



Global Trade Item Number

SKUGTIN
T13005-25G04061837337086
T13005-100G04061837337079
91214-5MG04061833238677