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Merck
CN

91240

Trichloroacetic acid solution

~6 M in H2O

Synonym(s):

TCA

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About This Item

Linear Formula:
Cl3CCOOH
CAS Number:
Molecular Weight:
163.39
UNSPSC Code:
12352200
Beilstein/REAXYS Number:
970119
MDL number:
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InChI key

YNJBWRMUSHSURL-UHFFFAOYSA-N

SMILES string

OC(=O)C(Cl)(Cl)Cl

InChI

1S/C2HCl3O2/c3-2(4,5)1(6)7/h(H,6,7)

grade

Molecular Biology

concentration

~6 M in H2O

impurities

DNases, none detected, Phosphatases, none detected, Proteases, none detected, RNases, none detected

solubility

H2O: 0.14 g/mL, clear, colorless

density

1.425 g/mL at 20 °C

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Biochem/physiol Actions

Trichloroacetic acid solution is traditionally used to precipitate protein. It can be used to determine protein concentration by quantitative precipitation. Trichloroacetic acid can also be used as a decalcifier and fixative in microscopy.

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J. Sambrook et al.
Molecular Cloning: A Laboratory Manual (1989)

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