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Merck
CN

91725

Trifluoroacetic acid pentafluorophenyl ester

purum, ≥95.0% (GC)

Synonym(s):

Pentafluorophenyl trifluoroacetate

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About This Item

Empirical Formula (Hill Notation):
C8F8O2
CAS Number:
Molecular Weight:
280.07
UNSPSC Code:
12352000
MDL number:
Beilstein/REAXYS Number:
2003848
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grade

purum

assay

≥95.0% (GC)

refractive index

n20/D 1.369

bp

128-133 °C (lit.)

density

1.625 g/mL at 20 °C (lit.)

SMILES string

Fc1c(F)c(F)c(OC(=O)C(F)(F)F)c(F)c1F

Other Notes

Reagent for the activation of carboxylic acids as pentafluorophenyl esters; Simultaneous protection (trifluoroacetyl) and activation (pentafluorophenyl) of amino (thio) acids


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L.M. Gayo et al.
Tetrahedron Letters, 37, 4915-4915 (1996)
M. Green et al.
Tetrahedron Letters, 31, 5851-5851 (1990)