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Merck
CN

92120

Sigma-Aldrich

Trimellitic anhydride

purum, ≥97.0% (T)

Synonym(s):

Benzene-1,2,4-tricarboxylic anhydride

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About This Item

Empirical Formula (Hill Notation):
C9H4O5
CAS Number:
552-30-7
Molecular Weight:
192.13
Beilstein:
9394
EC Number:
209-008-0
MDL number:
MFCD00005925
UNSPSC Code:
12162002
PubChem Substance ID:
329769867

Key Documents

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vapor density

6.6 (vs air)

vapor pressure

<0.01 mmHg ( 20 °C)

grade

purum

Assay

≥97.0% (T)

expl. lim.

7 %

mp

163-166 °C (lit.)
164-168 °C

SMILES string

OC(=O)c1ccc2C(=O)OC(=O)c2c1

InChI

1S/C9H4O5/c10-7(11)4-1-2-5-6(3-4)9(13)14-8(5)12/h1-3H,(H,10,11)

InChI key

SRPWOOOHEPICQU-UHFFFAOYSA-N

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Other Notes

This product has been replaced by B4600-ALDRICH | 1,2,4-Benzenetricarboxylic anhydride 97%

Signal Word

Danger

Hazard Statements

H317,H318,H334,H335

Hazard Classifications

Eye Dam. 1 - Resp. Sens. 1 - Skin Sens. 1 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

440.6 °F - closed cup

Flash Point(C)

227 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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M Henjakovic et al.
Toxicological sciences : an official journal of the Society of Toxicology, 106(2), 444-453 (2008-09-09)
A wide range of industrial chemicals can induce respiratory allergic reactions. Hence, there is an urgent need for methods identifying and characterizing the biological action of chemicals in the lung. Here, we present an easy, reliable alternative method to measure
Michèle Goutet et al.
Toxicology and applied pharmacology, 260(2), 95-104 (2012-03-03)
Identification of allergenic chemicals is an important occupational safety issue. While several methods exist to identify contact sensitizers, there is currently no validated model to predict the potential of chemicals to act as respiratory sensitizers. Previously, we reported that cytometry
Josje H E Arts et al.
Inhalation toxicology, 20(10), 935-948 (2008-08-01)
Irritant-induced inflammation of the airways may aggravate respiratory allergy induced by chemical respiratory allergens. Therefore, the effect of airway irritation by synthetic amorphous silica (SAS) on respiratory allergy to trimellitic anhydride (TMA) was studied. Brown Norway (BN) rats were topically
Claudia Schneider et al.
The Journal of investigative dermatology, 129(4), 899-907 (2008-10-03)
Due to the steadily increasing incidence of atopic dermatitis (AD), especially in children, there is a high medical need for new therapies and improved animal models. In mice, trimellitic anhydride (TMA) is routinely used to trigger T-cell-dependent contact hypersensitivity (CHS)
N J Holden et al.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 38(7), 1148-1159 (2008-05-24)
Chemical haptens induce both contact and allergic respiratory disease with dendritic cells (DCs) controlling and directing immune responses in vivo. Contact and respiratory haptens may promote differential cytokine production yet distinguishing these effects in vitro remains difficult due to human
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