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Merck
CN

92120

Trimellitic anhydride

purum, ≥97.0% (T)

Synonym(s):

Benzene-1,2,4-tricarboxylic anhydride

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About This Item

Empirical Formula (Hill Notation):
C9H4O5
CAS Number:
Molecular Weight:
192.13
EC Number:
209-008-0
UNSPSC Code:
12162002
PubChem Substance ID:
Beilstein/REAXYS Number:
9394
MDL number:
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InChI key

SRPWOOOHEPICQU-UHFFFAOYSA-N

InChI

1S/C9H4O5/c10-7(11)4-1-2-5-6(3-4)9(13)14-8(5)12/h1-3H,(H,10,11)

SMILES string

OC(=O)c1ccc2C(=O)OC(=O)c2c1

vapor density

6.6 (vs air)

vapor pressure

<0.01 mmHg ( 20 °C)

grade

purum

assay

≥97.0% (T)

expl. lim.

7 %

mp

163-166 °C (lit.), 164-168 °C

Other Notes

signalword

Danger

Hazard Classifications

Eye Dam. 1 - Resp. Sens. 1 - Skin Sens. 1 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

440.6 °F - closed cup

flash_point_c

227 °C - closed cup

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

Regulatory Information

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Jonathan A Bernstein et al.
Journal of occupational and environmental medicine, 53(10), 1122-1127 (2011-09-15)
Trimellitic anhydride (TMA) can elicit specific IgE-mediated immune responses leading to asthma. This single-blinded study investigated the ability of TMA skin testing to identify workers with TMA-serum specific IgE antibodies. Forty TMA-exposed workers who were previously screened for the presence
Subasri M Ayyadurai et al.
Analytical chemistry, 82(14), 6265-6272 (2010-06-22)
Continuous, on-site monitoring of personal exposure levels to occupational chemical hazards in ambient air is a long-standing analytical challenge. Such monitoring is required to institute appropriate health measures but is often limited by the time delays associated with batch air
L C Grammer et al.
Allergy and asthma proceedings, 18(4), 235-237 (1997-07-01)
Acid anhydrides such as trimellitic anhydride (TMA) are of interest due to their important industrial uses and to their adverse health effects in exposed populations. Important industrial uses of TMA include the production of epoxy and alkyd resins used to
Darrell R Boverhof et al.
Toxicological sciences : an official journal of the Society of Toxicology, 107(2), 427-439 (2008-12-02)
Genomic technologies have the potential to enhance and complement existing toxicology endpoints; however, assessment of these approaches requires a systematic evaluation including a robust experimental design with genomic endpoints anchored to traditional toxicology endpoints. The present study was conducted to
Min-Jung Bae et al.
Journal of ethnopharmacology, 144(3), 514-522 (2012-10-06)
Fenugreek (Trigonella foenum-graecum L.) has a wide variety of therapeutic properties for allergic and inflammatory diseases and is used as a traditional functional food, but its antiallergenic mechanism in these diseases is yet to be clearly elucidated. In the present

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