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Merck
CN

93353

TES

BioXtra, ≥99.0% (calc. based on dry substance, T)

Synonym(s):

2-[(2-Hydroxy-1,1-bis(hydroxymethyl)ethyl)amino]ethanesulfonic acid, N-[Tris(hydroxymethyl)methyl]-2-aminoethanesulfonic acid, TES free acid

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About This Item

Empirical Formula (Hill Notation):
C6H15NO6S
CAS Number:
Molecular Weight:
229.25
EC Number:
230-906-3
UNSPSC Code:
12161700
MDL number:
Beilstein/REAXYS Number:
1957061
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product line

BioXtra

assay

≥99.0% (calc. based on dry substance, T)

ign. residue

≤0.2% (as SO4)

loss

≤0.5% loss on drying, 110 °C

useful pH range

6.8-8.2, 7.0-8.0

pKa (20 °C)

7.5

pKa (25 °C)

7.5

mp

~225 °C (dec.)

solubility

H2O: 1 M at 20 °C, clear, colorless

anion traces

chloride (Cl-): ≤2000 mg/kg, sulfate (SO42-): ≤50 mg/kg

cation traces

Ca: ≤10 mg/kg, Cd: ≤5 mg/kg, Co: ≤5 mg/kg, Cr: ≤5 mg/kg, Cu: ≤5 mg/kg, Fe: ≤5 mg/kg, K: ≤200 mg/kg, Mg: ≤5 mg/kg, Mn: ≤5 mg/kg, Na: ≤200 mg/kg, Ni: ≤5 mg/kg, Pb: ≤5 mg/kg, Zn: ≤5 mg/kg

SMILES string

OCC(CO)(CO)NCCS(O)(=O)=O

InChI

1S/C6H15NO6S/c8-3-6(4-9,5-10)7-1-2-14(11,12)13/h7-10H,1-5H2,(H,11,12,13)

InChI key

JOCBASBOOFNAJA-UHFFFAOYSA-N

Other Notes

Biological buffer


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Storage Class

13 - Non Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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W J Holmgren et al.
Journal of in vitro fertilization and embryo transfer : IVF, 6(4), 207-212 (1989-08-01)
Penetration of zona-free hamster oocytes by human spermatozoa after preincubation with BWW medium (standard technique) or a buffer system containing egg yolk (TESTY) was compared by applying both treatments to aliquots of 60 ejaculates from 34 patients. The TESTY-treated spermatozoa
Yikang Wu et al.
Organic letters, 4(13), 2141-2144 (2002-06-21)
[reaction: see text] In DMSO cleavage of triethylsilyl (TES) ethers by o-iodoxybenzoic acid (IBX) was significantly faster than cleavage of tert-butyldimethylsilyl (TBS) ethers or further oxidation into carbonyl compounds. In most cases, TES protecting groups could be removed in good
R H Martin et al.
Biology of reproduction, 47(2), 268-270 (1992-08-01)
Human sperm karyotypes can be prepared after fusion of human sperm with Golden hamster oocytes. Most laboratories use one of two methods of sperm capacitation: incubation of freshly-ejaculated sperm in Biggers, Whitten, and Whittingham (BWW) medium for 5-7 h at