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Merck
CN

93353

TES

BioXtra, ≥99.0% (calc. based on dry substance, T)

Synonym(s):

2-[(2-Hydroxy-1,1-bis(hydroxymethyl)ethyl)amino]ethanesulfonic acid, N-[Tris(hydroxymethyl)methyl]-2-aminoethanesulfonic acid, TES free acid

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About This Item

Empirical Formula (Hill Notation):
C6H15NO6S
CAS Number:
7365-44-8
Molecular Weight:
229.25
EC Number:
230-906-3
UNSPSC Code:
12161700
MDL number:
MFCD00007532
Beilstein/REAXYS Number:
1957061

Key Documents

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InChI

1S/C6H15NO6S/c8-3-6(4-9,5-10)7-1-2-14(11,12)13/h7-10H,1-5H2,(H,11,12,13)

InChI key

JOCBASBOOFNAJA-UHFFFAOYSA-N

SMILES string

OCC(CO)(CO)NCCS(O)(=O)=O

product line

BioXtra

assay

≥99.0% (calc. based on dry substance, T)

ign. residue

≤0.2% (as SO4)

loss

≤0.5% loss on drying, 110 °C

useful pH range

6.8-8.2, 7.0-8.0

pKa (20 °C)

7.5

pKa (25 °C)

7.5

mp

~225 °C (dec.)

solubility

H2O: 1 M at 20 °C, clear, colorless

anion traces

chloride (Cl-): ≤2000 mg/kg, sulfate (SO42-): ≤50 mg/kg

cation traces

Ca: ≤10 mg/kg, Cd: ≤5 mg/kg, Co: ≤5 mg/kg, Cr: ≤5 mg/kg, Cu: ≤5 mg/kg, Fe: ≤5 mg/kg, K: ≤200 mg/kg, Mg: ≤5 mg/kg, Mn: ≤5 mg/kg, Na: ≤200 mg/kg, Ni: ≤5 mg/kg, Pb: ≤5 mg/kg, Zn: ≤5 mg/kg

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Other Notes

Biological buffer

Storage Class

13 - Non Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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W J Holmgren et al.
Journal of in vitro fertilization and embryo transfer : IVF, 6(4), 207-212 (1989-08-01)
Penetration of zona-free hamster oocytes by human spermatozoa after preincubation with BWW medium (standard technique) or a buffer system containing egg yolk (TESTY) was compared by applying both treatments to aliquots of 60 ejaculates from 34 patients. The TESTY-treated spermatozoa
U Kragh-Hansen et al.
Clinical chemistry, 39(2), 202-208 (1993-02-01)
We examined the suitability of nine organic buffers for studying calcium binding to albumin by equilibrium dialysis. Results obtained with defatted human serum albumin showed that 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid (HEPES) and 2-([tris(hydroxymethyl)methyl] amino)ethanesulfonic acid were superior. Scatchard analysis of the experimental
G S Prins et al.
Fertility and sterility, 46(1), 147-149 (1986-07-01)
Several cryoprotective media currently in use for human sperm cryopreservation have been directly compared with each other by use of a static vapor freezing technique. The TEST-citrate-yolk buffers with glycerol resulted in the highest motility and longevity after thawing; thus
S J Paterson et al.
Journal of pharmacological methods, 23(4), 275-283 (1990-07-01)
In homogenates of guinea-pig brain minus cerebellum, the delta-binding of 1.5 nM [3H]-[D-Pen2,D-Pen5]enkephalin is little affected by the type and concentration of the three buffers, Tris-HCl, HEPES-KOH, or TES-KOH (10-75 mM). However, the mu-binding of 1 nM [3H]-[D]Ala2,MePhe4,Gly-ol5]enkephalin or the
J Taylor et al.
Pflugers Archiv : European journal of physiology, 442(2), 256-262 (2001-06-22)
We used the Ussing short-circuit technique to investigate the role of HCO3- in the adenosine 3',5'-cyclic monophosphate (cAMP)-dependent secretory response of the human distal colon. In HCO3(-)-free 4-(2-hydroxyethyl)-1-piperazineethanesulphonic acid (HEPES)-Ringer's, forskolin (10 mumol l-1 mucosal and serosal) evoked a sustained
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