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Merck
CN

93357

TAPSO

≥99.0% (T)

Synonym(s):

2-Hydroxy-3-[tris(hydroxymethyl)methylamino]-1-propanesulfonic acid, N-[Tris(hydroxymethyl)methyl]-3-amino-2-hydroxypropanesulfonic acid

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About This Item

Empirical Formula (Hill Notation):
C7H17NO7S
CAS Number:
Molecular Weight:
259.28
EC Number:
269-993-8
UNSPSC Code:
12161700
Beilstein/REAXYS Number:
2113949
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assay

≥99.0% (T)

impurities

≤1% water

ign. residue

≤0.1%

useful pH range

7.0-8.2

pKa (20 °C)

7.55

pKa (25 °C)

7.6

mp

224-229 °C (dec.)

solubility

H2O: 0.5 M at 20 °C, clear, colorless

anion traces

chloride (Cl-): ≤100 mg/kg, sulfate (SO42-): ≤50 mg/kg

cation traces

Ca: ≤10 mg/kg, Cd: ≤5 mg/kg, Co: ≤5 mg/kg, Cr: ≤5 mg/kg, Cu: ≤5 mg/kg, Fe: ≤10 mg/kg, K: ≤50 mg/kg, Mg: ≤5 mg/kg, Mn: ≤5 mg/kg, Na: ≤100 mg/kg, Ni: ≤5 mg/kg, Pb: ≤5 mg/kg, Zn: ≤5 mg/kg

SMILES string

OCC(CO)(CO)NCC(O)CS(O)(=O)=O

InChI

1S/C7H17NO7S/c9-3-7(4-10,5-11)8-1-6(12)2-16(13,14)15/h6,8-12H,1-5H2,(H,13,14,15)

InChI key

RZQXOGQSPBYUKH-UHFFFAOYSA-N

Other Notes

New zwitterionic hydrogen buffer for biological research

Disclaimer

According to Ferreira, et al., TAPSO can have a strong interaction with iron in solution. Based on this citation, it is recommended to use plastic-coated or PTFE-coated utensils when working with this chemical.

Regulatory Information

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Hydrogen ion buffers for biological research.
W J Ferguson et al.
Analytical biochemistry, 104(2), 300-310 (1980-05-15)
(Un)suitability of the use of pH buffers in biological, biochemical and environmental studies and their interaction with metal ions - a review.
Ferreira C.M.H. et al.
Royal Society of Chemistry Advances, 5, 30989-31003 (2015)
(Un)suitability of the use of pH buffers in biological, biochemical and environmental studies and their interaction with metal ions ? a review.
Ferreira, C.M.H., et al.
Royal Society of Chemistry Advances, 5, 30989-31003 (2015)

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