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Merck
CN

93730

L-Tryptophan methyl ester hydrochloride

puriss., ≥99.0% (AT)

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About This Item

Empirical Formula (Hill Notation):
C12H14N2O2 · HCl
CAS Number:
Molecular Weight:
254.71
EC Number:
231-385-5
UNSPSC Code:
12352200
PubChem Substance ID:
Beilstein/REAXYS Number:
4240280
MDL number:
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grade

puriss.

assay

≥99.0% (AT)

optical activity

[α]20/D +18±1°, c = 3% in methanol

mp

218-220 °C (lit.), ~220 °C (dec.)

SMILES string

Cl.COC(=O)[C@@H](N)Cc1c[nH]c2ccccc12

InChI

1S/C12H14N2O2.ClH/c1-16-12(15)10(13)6-8-7-14-11-5-3-2-4-9(8)11;/h2-5,7,10,14H,6,13H2,1H3;1H/t10-;/m0./s1

InChI key

XNFNGGQRDXFYMM-PPHPATTJSA-N

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Storage Class

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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Christine Böttcher et al.
Journal of experimental botany, 62(12), 4267-4280 (2011-05-06)
Nine Gretchen Hagen (GH3) genes were identified in grapevine (Vitis vinifera L.) and six of these were predicted on the basis of protein sequence similarity to act as indole-3-acetic acid (IAA)-amido synthetases. The activity of these enzymes is thought to
Patrick P C Boor et al.
European journal of immunology, 41(6), 1663-1674 (2011-04-07)
Allo-reactive memory T cells are a major barrier for induction of immunological tolerance to allografts in humans. Here, we report that stimulation of unfractionated human T cells with TLR-stimulated allogeneic plasmacytoid dendritic cells (pDCs) induces CD8(+) regulatory T cells (Tregs)
Vijay Narayan Tiwari et al.
Journal of child neurology, 27(5), 598-603 (2011-12-06)
In this study, we determined whether diffusion tensor imaging (DTI), a more widely available imaging modality, is as effective as α-[(11)C]methyl-l-tryptophan (AMT)-positron emission tomography (PET) in localizing epileptogenic tubers in tuberous sclerosis complex. Following that, coregistration of AMT-PET and diffusion
Michael Behen et al.
Movement disorders : official journal of the Movement Disorder Society, 22(15), 2256-2262 (2007-08-22)
Symptoms in Tourette syndrome (TS) are likely related to abnormalities involving multiple neurotransmitter systems in striatal-thalamo-cortical circuitry. Although prior studies have found abnormal levels of tryptophan, serotonin, and their metabolites in blood, cerebrospinal fluid and brain tissue of TS patients
Massoud Akhtari et al.
Epilepsia, 49(8), 1419-1430 (2008-05-16)
The development of nonradioactive and targeted magnetonanoparticles (MNP) capable of crossing the blood-brain barrier (BBB) and of concentrating in the epileptogenic tissues of acute and chronic animal models of temporal lobe epilepsy to render these tissues visible on magnetic resonance

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