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Merck
CN

95250

DL-α-Tocopherol acetate

≥97.0% (HPLC), 1 U/mg

Synonym(s):

Vitamin E acetate, all-rac-α-Tocopheryl acetate

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About This Item

Empirical Formula (Hill Notation):
C31H52O3
CAS Number:
Molecular Weight:
472.74
EC Number:
231-710-0
UNSPSC Code:
12352200
MDL number:
Beilstein/REAXYS Number:
97512
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assay

≥97.0% (HPLC)

specific activity

1 U/mg

impurities

≤0.02% heavy metals, ≤1.0% free tocopherol

ign. residue

≤0.1%

refractive index

n20/D 1.497

density

0.96 g/mL at 20 °C (lit.)

storage temp.

2-8°C

SMILES string

CC(C)CCC[C@@H](C)CCC[C@@H](C)CCC[C@]1(C)CCc2c(C)c(OC(C)=O)c(C)c(C)c2O1

InChI

1S/C31H52O3/c1-21(2)13-10-14-22(3)15-11-16-23(4)17-12-19-31(9)20-18-28-26(7)29(33-27(8)32)24(5)25(6)30(28)34-31/h21-23H,10-20H2,1-9H3/t22-,23-,31-/m1/s1

InChI key

ZAKOWWREFLAJOT-CEFNRUSXSA-N

Other Notes

1 U corresponds to 1 USP-U acc. USP XXIII, 1631 (1995)


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Storage Class

10 - Combustible liquids

wgk

WGK 1

flash_point_f

No data available

flash_point_c

No data available

ppe

Eyeshields, Gloves

Regulatory Information

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Marco Marenchino et al.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 21(2-3), 313-321 (2004-02-06)
Phopholipidosis is a lipid storage disorder caused by cationic amphiphilic drugs (CADs) characterized by the lysosomal accumulation of phospholipids and drug. alpha-Tocopherol (alpha-Toc) has a reversible effect on phospholipidosis in rats and cell culture. We studied the influence of alpha-Toc
Kristin I Løken-Amsrud et al.
PloS one, 8(1), e54417-e54417 (2013-01-26)
Alpha-tocopherol is the main vitamin E compound in humans, and has important antioxidative and immunomodulatory properties. The aim of this study was to study alpha-tocopherol concentrations and their relationship to disease activity in Norwegian multiple sclerosis (MS) patients. Prospective cohort
Katharina M Espe et al.
Clinical journal of the American Society of Nephrology : CJASN, 8(3), 452-458 (2013-01-22)
Trials with the antioxidant vitamin E have failed to show benefit in the general population. Considering the different causes of death in ESRD, this study investigated the association between plasma concentrations of α-tocopherol and specific clinical outcomes in diabetic hemodialysis



Global Trade Item Number

SKUGTIN
PHR1919-500MG04061835220878
C4397-25G04061833492093
C4397-100G04061832574141
1130505-350MG04061833842386