96093
Zearalenone
≥98.0% (TLC)
Synonym(s):
F-2 toxin
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About This Item
Empirical Formula (Hill Notation):
C18H22O5
CAS Number:
Molecular Weight:
318.36
UNSPSC Code:
12352200
Beilstein/REAXYS Number:
1350216
MDL number:
assay
≥98.0% (TLC)
application(s)
cleaning products
cosmetics
food and beverages
personal care
SMILES string
C[C@H]1CCCC(=O)CCC\C=C\c2cc(O)cc(O)c2C(=O)O1
InChI
1S/C18H22O5/c1-12-6-5-9-14(19)8-4-2-3-7-13-10-15(20)11-16(21)17(13)18(22)23-12/h3,7,10-12,20-21H,2,4-6,8-9H2,1H3/b7-3+/t12-/m0/s1
InChI key
MBMQEIFVQACCCH-QBODLPLBSA-N
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Biochem/physiol Actions
Zearalenone, a fungal mycotoxin produced by Fusarium, binds the estrogen receptor (ER) and is uterotropic in the newborn rat. It is a common contaminant in cereal grain used for animal and human food, and exerts an estrogenic activity that modulates/disrupts endocrine function in animals and possibly humans.
Regulatory Information
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Thomas J Turbyville et al.
Journal of natural products, 69(2), 178-184 (2006-02-28)
In an effort to discover small molecule inhibitors of Hsp90, we have screened over 500 EtOAc extracts of Sonoran desert plant-associated fungi using a two-stage strategy consisting of a primary cell-based heat shock induction assay (HSIA) followed by a secondary
Dojin Ryu et al.
Advances in experimental medicine and biology, 504, 205-216 (2002-04-02)
Zearalenone (ZEN), a common contaminant of all major cereal grains worldwide, is produced by some plant pathogenic molds including Fusarium graminearum and F. culmorum. The biological activity of this mycotoxin is mainly attributed to its estrogenic activity that modulates/disrupts endocrine
Sloan Ayers et al.
Journal of natural products, 74(5), 1126-1131 (2011-04-26)
As part of our ongoing investigation of filamentous fungi for anticancer leads, an active fungal extract was identified from the Mycosynthetix library (MSX 63935; related to Phoma sp.). The initial extract exhibited cytotoxic activity against the H460 (human non-small cell
Tobias J Zimmermann et al.
Bioorganic & medicinal chemistry, 17(2), 530-536 (2008-12-23)
In order to extend the chemical diversity available for organic polyketide synthesis, the concept of propionate scanning was developed. We observed that naturally occurring polyketides frequently comprise not only acetate, but also some propionate as building blocks. Therefore our approach
Global Trade Item Number
| SKU | GTIN |
|---|---|
| W513504-SAMPLE | 04061838194350 |
| S5006-100G-A | 04061836933951 |
| S5006-5G-A | 04061836934545 |
| 8032020250 | 04022536378893 |
| 8032020025 | 04027269075514 |
| S5006-500G-A | 04061836934439 |
| S5006-1KG-A | 04061837757136 |
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