Skip to Content
Merck
CN

C0414

Clidinium bromide

analytical standard

Synonym(s):

3-Hydroxy-1-methylquinuclidinium bromide benzilate, 3-[(Hydroxydiphenylacetyl)oxy]-1-methyl-1-azoniabicyclo[2.2.2]octane bromide

Sign In to View Organizational & Contract Pricing.

Select a Size

About This Item

Empirical Formula (Hill Notation):
C22H26BrNO3
CAS Number:
3485-62-9
Molecular Weight:
432.35
NACRES:
NA.24
PubChem Substance ID:
329774786
UNSPSC Code:
41116107
EC Number:
222-471-3
MDL number:
MFCD00078996

Key Documents

View All Documentation
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

grade

analytical standard

Quality Level

200

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

format

neat

SMILES string

Br.C[N]12CCC(CC1)C(C2)OC(=O)C(O)(c3ccccc3)c4ccccc4

InChI

1S/C22H26NO3.BrH/c1-23-14-12-17(13-15-23)20(16-23)26-21(24)22(25,18-8-4-2-5-9-18)19-10-6-3-7-11-19;/h2-11,17,20,25H,12-16H2,1H3;1H

InChI key

WVDSMJSQJXGCNY-UHFFFAOYSA-N

General description

Clidinium bromide is an anticholinergic, antisecretory and antispasmodic drug, widely used in treating anxiety-related conditions and spastic colon by inhibiting the action of parasympathetic innervations thus decreasing the secretions of stomach acid and slowing the intestines.

Application

Clidinium bromide has been used as an analytical standard for the quantification of the analyte in pharmaceutical formulations using different analytical techniques.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our Documents section.

If you need assistance, please contact Customer Support

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

F Brunner et al.
British journal of pharmacology, 102(2), 373-380 (1991-02-01)
1. Muscarinic receptors on endothelial cells of bovine thoracic aorta were characterized by binding assays in which (-)-[3H]-N-methyl quinuclidinyl benzilate ([3H]-NMeQNB) was used as radioligand. 2. Binding of [3H]-NMeQNB to crude membranes of freshly isolated endothelial cells was atropine-displaceable and
Simultaneous determination of chlordiazepoxide and clidinium bromide in pharmaceutical formulations by derivative spectrophotometry
Toral I.M, et al.
The Veterinary Quarterly, 189(1), 67-74 (1999)
H Valette et al.
European journal of pharmacology, 306(1-3), 133-138 (1996-06-13)
The muscarinic receptor antagonist methyl-quinuclidinyl-benzylate decreased myocardial beta-adrenoceptor density Bmax: 20.4 +/- 2.4 pmol/ml tissue versus 33.3 +/- 4 pmol/ml tissue in control dogs (P < 0.001), as assessed by using [11C]CGP-12177 (((2S)-4-(3-t-butyl-amino-2 hydroxypropoxy)-benzimidazol-2-one)) and positron emission tomography. In contrast
C A Otto et al.
International journal of radiation applications and instrumentation. Part B, Nuclear medicine and biology, 18(5), 557-561 (1991-01-01)
The localization of quaternized muscarinic receptor (mAChR) antagonists, [11C]methyl tropanyl benzilate ([11C]MTRB) and [11C]methyl quinuclidinyl benzilate ([11C]MQNB), in rat pituitary was compared to that of [11C]tropanyl benzilate ([11C]TRB), a neutral antagonist. The quaternized ligands localize via a mAChR-mediated mechanism as
E Malatynska et al.
Brain research bulletin, 47(3), 285-290 (1998-12-29)
Three chimeric receptors stably expressed in murine fibroblast (B82) cells were used to examine how different parts of the rat muscarinic m1 and m2 receptors contribute to the down-regulation process. The MCH7 chimeric m2 receptor contained a fragment between VIth
View All Related Papers

Global Trade Item Number

SKUGTIN
C0414-1G04061826690031

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service