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I3132

Indoprofen

analytical standard

Synonym(s):

α-Methyl-p-(1-oxo-2-isoindolinyl)benzeneacetic acid

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About This Item

Empirical Formula (Hill Notation):
C17H15NO3
CAS Number:
31842-01-0
Molecular Weight:
281.31
NACRES:
NA.24
PubChem Substance ID:
329815369
UNSPSC Code:
41116107
EC Number:
250-833-0
MDL number:
MFCD00057144
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grade

analytical standard

Quality Level

200

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

format

neat

SMILES string

CC(C(O)=O)c1ccc(cc1)N2Cc3ccccc3C2=O

InChI

1S/C17H15NO3/c1-11(17(20)21)12-6-8-14(9-7-12)18-10-13-4-2-3-5-15(13)16(18)19/h2-9,11H,10H2,1H3,(H,20,21)

InChI key

RJMIEHBSYVWVIN-UHFFFAOYSA-N

Gene Information

human ... IL8RA(3577), PTGS1(5742), PTGS2(5743)

Application

Indoprofen is a non-steroidal drug, which can show a range of pharmacological properties such as analgesic and anti-inflammatory activities.
Indoprofen is a non-steroidal drug, which can show a range of pharmacological properties such as analgesic and anti-inflammatory activities. Its mode of action involves the inhibition of prostaglandin synthesis.
Indoprofen may be used as an analytical reference standard for the quantification of the analyte in biological samples and pharmaceutical formulations using different chromatography techniques.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

signalword

Danger

hcodes

H301,H351

Hazard Classifications

Acute Tox. 3 Oral - Carc. 2

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

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Certificates of Analysis (COA)

Lot/Batch Number
127F0834V
127F0834

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M Kurowski et al.
International journal of clinical pharmacology research, 8(4), 287-293 (1988-01-01)
Twenty-four patients suffering from rheumatoid arthritis and requiring articular punctures were treated with 200 mg of indoprofen thrice daily for four days. The subjects were divided into four groups each of six patients. Following the last dose, blood and synovial
P Failli et al.
British journal of pharmacology, 123(7), 1457-1463 (1998-05-14)
1. The effect of the NSAIDs indomethacin, indoprofen, diclofenac and acetylsalicylic acid on the increase in guanosine 3':5'-cyclic monophosphate (cyclic GMP) induced by nitric oxide-donor agents was tested in human whole platelets and in platelet crude homogenate. 2. In whole
Pharmacokinetics of the enantiomers of indoprofen in man
V T, et al.
International Journal of Clinical Pharmacology Research, 4(3), 223-230 (1984)
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