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I3132

Indoprofen

analytical standard

Synonym(s):

α-Methyl-p-(1-oxo-2-isoindolinyl)benzeneacetic acid

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About This Item

Empirical Formula (Hill Notation):
C17H15NO3
CAS Number:
31842-01-0
Molecular Weight:
281.31
NACRES:
NA.24
PubChem Substance ID:
329815369
UNSPSC Code:
41116107
EC Number:
250-833-0
MDL number:
MFCD00057144
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grade

analytical standard

Quality Level

200

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

format

neat

SMILES string

CC(C(O)=O)c1ccc(cc1)N2Cc3ccccc3C2=O

InChI

1S/C17H15NO3/c1-11(17(20)21)12-6-8-14(9-7-12)18-10-13-4-2-3-5-15(13)16(18)19/h2-9,11H,10H2,1H3,(H,20,21)

InChI key

RJMIEHBSYVWVIN-UHFFFAOYSA-N

Gene Information

human ... IL8RA(3577), PTGS1(5742), PTGS2(5743)

Application

Indoprofen is a non-steroidal drug, which can show a range of pharmacological properties such as analgesic and anti-inflammatory activities.
Indoprofen is a non-steroidal drug, which can show a range of pharmacological properties such as analgesic and anti-inflammatory activities. Its mode of action involves the inhibition of prostaglandin synthesis.
Indoprofen may be used as an analytical reference standard for the quantification of the analyte in biological samples and pharmaceutical formulations using different chromatography techniques.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

signalword

Danger

hcodes

H301,H351

Hazard Classifications

Acute Tox. 3 Oral - Carc. 2

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

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Certificates of Analysis (COA)

Lot/Batch Number
127F0834V
127F0834

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P Failli et al.
British journal of pharmacology, 123(7), 1457-1463 (1998-05-14)
1. The effect of the NSAIDs indomethacin, indoprofen, diclofenac and acetylsalicylic acid on the increase in guanosine 3':5'-cyclic monophosphate (cyclic GMP) induced by nitric oxide-donor agents was tested in human whole platelets and in platelet crude homogenate. 2. In whole
Determination of the enantiomers of indoprofen in blood plasma by high-performance liquid chromatography after rapid derivatization by means of ethyl chloroformate
Bjorkman S
Journal of Chromatography. B, Biomedical Applications, 339(2), 339-346 (1985)
B Przybilla et al.
Photo-dermatology, 4(2), 73-78 (1987-04-01)
The phototoxic activity of the non-steroidal anti-inflammatory drugs (NSAID) acetylsalicylic acid, benoxaprofen, carprofen, diclofenac, indoprofen, ketoprofen, tiaprofenic acid, and of thiophene, a heterocyclic ring structure of the tiaprofenic acid molecule, was evaluated in vitro by a newly developed photo-basophil-histamine-release test
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