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Merck
CN

P1254

Brij® L23

suitable for Stein-Moore chromatography

Synonym(s):

Brij 35, C12E23, Polyoxyethylene (23) lauryl ether

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About This Item

CAS Number:
NACRES:
NA.21
PubChem Substance ID:
UNSPSC Code:
12161900
MDL number:
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description

non-ionic

Quality Level

form

solid

mol wt

micellar avg mol wt 48,000, estimated mol wt 1198

aggregation number

20-40

CMC

91 μM

transition temp

cloud point >100 °C

HLB

16.9

suitability

suitable for Stein-Moore chromatography

SMILES string

CCCCCCCCCCCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO

InChI

1S/C58H118O24/c1-2-3-4-5-6-7-8-9-10-11-13-60-15-17-62-19-21-64-23-25-66-27-29-68-31-33-70-35-37-72-39-41-74-43-45-76-47-49-78-51-53-80-55-57-82-58-56-81-54-52-79-50-48-77-46-44-75-42-40-73-38-36-71-34-32-69-30-28-67-26-24-65-22-20-63-18-16-61-14-12-59/h59H,2-58H2,1H3

InChI key

IEQAICDLOKRSRL-UHFFFAOYSA-N

Application

Non-ionic detergent. Useful for the extraction of membrane proteins. Typically used in the range of 0.1-1%.

Legal Information

Brij is a registered trademark of Croda International PLC


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Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

>300.2 °F - open cup

flash_point_c

> 149 °C - open cup

ppe

dust mask type N95 (US), Eyeshields, Gloves



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K Yamamoto et al.
Biochimica et biophysica acta, 790(3), 208-218 (1984-11-09)
Two forms of an acid proteinase have been purified from human erythrocyte membranes by a simple method involving selective extraction with 0.5% Brij 35, affinity chromatography on pepstatin A-Sepharose 4B, and chromatography on Sephacryl S-200 and DEAE-Sephadex G-100. One species
T Tobimatsu et al.
Archives of biochemistry and biophysics, 347(1), 132-140 (1997-11-05)
Recombinant adenosylcobalamin-dependent diol dehydratase of Klebsiella oxytoca overexpressed in Escherichia coli was purified to homogeneity. The enzyme has a low solubility and was extracted from the crude membrane fraction with 1% Brij 35 in a high recovery. Subsequent chromatography on
G C Valenzuela et al.
European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery, 46(5), 593-599 (2013-09-28)
Sclerosant foams are aqueous and break down under the influence of gravity, pressure, and temperature. The aim of this study was to investigate the effects of temperature on foam stability. Sodium tetradecyl sulphate (STS) and polidocanol (POL) liquid and foam



Global Trade Item Number

SKUGTIN
P1254-5KG04061833612538
P1254-500G04061834354284