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T6159

Trimebutine

analytical standard

Synonym(s):

3,4,5-Trimethoxybenzoic acid 2-(dimethylamino)-2-phenylbutyl ester

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About This Item

Empirical Formula (Hill Notation):
C22H29NO5
CAS Number:
39133-31-8
Molecular Weight:
387.47
NACRES:
NA.24
PubChem Substance ID:
329826841
UNSPSC Code:
41116107
EC Number:
254-309-2
MDL number:
MFCD00133873
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grade

analytical standard

Quality Level

200

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

format

neat

storage temp.

2-8°C

SMILES string

CCC(COC(=O)c1cc(OC)c(OC)c(OC)c1)(N(C)C)c2ccccc2

InChI

1S/C22H29NO5/c1-7-22(23(2)3,17-11-9-8-10-12-17)15-28-21(24)16-13-18(25-4)20(27-6)19(14-16)26-5/h8-14H,7,15H2,1-6H3

InChI key

LORDFXWUHHSAQU-UHFFFAOYSA-N

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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M Delvaux et al.
The Journal of international medical research, 25(5), 225-246 (1997-11-19)
The actions of trimebutine [3,4,5-trimethoxybenzoic acid 2-(dimethylamino)-2-phenylbutylester] on the gastrointestinal tract are mediated via (i) an agonist effect on peripheral mu, kappa and delta opiate receptors and (ii) release of gastrointestinal peptides such as motilin and modulation of the release
Véronique Vitton et al.
World journal of gastroenterology, 18(14), 1610-1615 (2012-04-25)
To report the results of a medical management of sphincter of oddi dysfunction (SOD) after an intermediate follow-up period. A total of 59 patients with SOD (2 men and 57 women, mean age 51 years old) were included in this
Shiho Okano et al.
Journal of pharmacological sciences, 98(4), 411-418 (2005-08-05)
Stress-induced colonic functional changes have been investigated mainly under conditions involving physical stress, like in the restraint stress model. In this study, we established a new stress-induced defecation model involving the placement of Mongolian gerbils in a novel environment (novelty
[Trimebutine. Pharmacology, recent concepts about its mechanism of action, therapeutic results].
B Fraitag et al.
Gastroenterologie clinique et biologique, 16(5), 413-420 (1992-01-01)
O Bekem et al.
Acta gastro-enterologica Belgica, 68(4), 416-418 (2006-01-26)
Of the feeding disorders in children, poor appetite is probably one of the most common complaints notified by parents. Since gastric motility disorders may be the cause of this symptom, the aim of our study was to investigate the effect
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