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Y0000259

Diclazuril for system suitability

Name: Diclazuril for system suitability
Brand: SIAL

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

2,6-Dichloro-α-(4-chlorophenyl)-4-[4,5-dihydro-3,5-dioxo-1,2,4-triazin-2(3H)-yl]benzeneacetonitrile

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About This Item

Empirical Formula (Hill Notation):

C₁₇H₉Cl₃N₄O₂

CAS Number:

101831-37-2

Molecular Weight:

407.64

NACRES:

NA.24

PubChem Substance ID:

329830893

UNSPSC Code:

41116107

MDL number:

MFCD00867203

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Properties

grade

pharmaceutical primary standard

API family

diclazuril

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

Clc1ccc(cc1)C(C#N)c2c(Cl)cc(cc2Cl)N3N=CC(=O)NC3=O

InChI

1S/C17H9Cl3N4O2/c18-10-3-1-9(2-4-10)12(7-21)16-13(19)5-11(6-14(16)20)24-17(26)23-15(25)8-22-24/h1-6,8,12H,(H,23,25,26)

InChI key

ZSZFUDFOPOMEET-UHFFFAOYSA-N

Description

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Diclazuril for system suitability EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

pictograms

GHS08

signalword

Warning

hcodes

H361d,H373

pcodes

P202 - P260 - P280 - P308 + P313 - P405 - P501

Hazard Classifications

Repr. 2 - STOT RE 2

target_organs

Lungs,Liver,lymph node

Storage Class

11 - Combustible Solids

wgk

WGK 2

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Control strategies using diclazuril against coccidiosis in goat kids.

Antonio Ruiz et al.

Parasitology research, 110(6), 2131-2136 (2011-12-24)

Coccidiosis is probably the main parasitic disease affecting goat kids around the weaning period, leading to high economic losses in goat production due to deaths and delayed growth rates of infected animals. A total of 101 kids of 2-4 weeks

Receptor for activated C kinase ortholog of second-generation merozoite in Eimeria tenella: clone, characterization, and diclazuril-induced mRNA expression.

Bian-hua Zhou et al.

Parasitology research, 111(4), 1447-1455 (2012-07-04)

The receptor for activated C kinase (RACK) cDNA of second-generation merozoites of Eimeria tenella was cloned using reverse transcriptase polymerase chain reaction and rapid amplification of cDNA ends, compared with other species, and then successfully expressed using the pET-28a vector

Effects of diclazuril on apoptosis and mitochondrial transmembrane potential in second-generation merozoites of Eimeria tenella.

Bianhua Zhou et al.

Veterinary parasitology, 168(3-4), 217-222 (2009-12-17)

Diclazuril, a benzeneacetonitrile anticoccidial agent, has potent activity against various stages of Eimeria tenella (E. tenella). To study the effects of diclazuril on E. tenella merozoites, purified second-generation merozoites were obtained from infected chicken caecal tissue at 120h after inoculation

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Global Trade Item Number

SKU	GTIN
Y0000259	04061837568114