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Y0001525

Basic butylated methacrylate copolyme

Name: Basic butylated methacrylate copolyme
Brand: SIAL

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

2-Methyl-2-propenoic acid butyl ester polymer with 2-(dimethylamino)ethyl 2-methyl-2-propenoate and methyl 2-methyl-2-propenoate

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About This Item

CAS Number:

24938-16-7

UNSPSC Code:

41116107

NACRES:

NA.24

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Properties

grade

pharmaceutical primary standard

API family

copolymers, butylated methacrylate copolymer

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

N(CCOC(=O)C(=C)C)(C)C.O(CCCC)C(=O)C(=C)C.O(C)C(=O)C(=C)C

InChI

1S/C8H15NO2.C8H14O2.C5H8O2/c1-7(2)8(10)11-6-5-9(3)4;1-4-5-6-10-8(9)7(2)3;1-4(2)5(6)7-3/h1,5-6H2,2-4H3;2,4-6H2,1,3H3;1H2,2-3H3

InChI key

NEDGUIRITORSKL-UHFFFAOYSA-N

Description

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Basic butylated methacrylate copolyme EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

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Characterization of the epithelial permeation enhancing effect of basic butylated methacrylate copolymer--in vitro studies.

Stefan Grube et al.

Biomacromolecules, 9(5), 1398-1405 (2008-04-15)

Membrane destabilizing properties and increased efflux of doxorubicin from liposomes caused by basic butylated methacrylate copolymer (BBMC), better known under its commercial trade name EUDRAGIT E, have been described in the scientific literature. Here, we investigated the effect of BBMC

Aminoalkyl methacrylate copolymers for improving the solubility of tacrolimus. I: Evaluation of solid dispersion formulations.

Takatsune Yoshida et al.

International journal of pharmaceutics, 428(1-2), 18-24 (2012-03-13)

The aim of this study was to investigate the effect of Eudragit E/HCl (E-SD) on the reprecipitation of a poorly water-soluble drug, tacrolimus. To evaluate the inhibition of reprecipitation of E-SD, reprecipitation studies on tacrolimus were conducted using a dissolution

Characterisation of solid dispersions of paracetamol and EUDRAGIT E prepared by hot-melt extrusion using thermal, microthermal and spectroscopic analysis.

Sheng Qi et al.

International journal of pharmaceutics, 354(1-2), 158-167 (2008-02-05)

Hot-melt extrusion has attracted considerable interest within the pharmaceutical industry. However, there remains some uncertainty as to how to characterise the physical structure of the extruded systems, particularly in terms of identifying the nature of the drug dispersion within the

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Global Trade Item Number

SKU	GTIN
Y0001525	04061833818657