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Merck
CN

Y0001525

Basic butylated methacrylate copolyme

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

2-Methyl-2-propenoic acid butyl ester polymer with 2-(dimethylamino)ethyl 2-methyl-2-propenoate and methyl 2-methyl-2-propenoate

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About This Item

CAS Number:
UNSPSC Code:
41116107
NACRES:
NA.24
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SMILES string

N(CCOC(=O)C(=C)C)(C)C.O(CCCC)C(=O)C(=C)C.O(C)C(=O)C(=C)C

InChI

1S/C8H15NO2.C8H14O2.C5H8O2/c1-7(2)8(10)11-6-5-9(3)4;1-4-5-6-10-8(9)7(2)3;1-4(2)5(6)7-3/h1,5-6H2,2-4H3;2,4-6H2,1,3H3;1H2,2-3H3

InChI key

NEDGUIRITORSKL-UHFFFAOYSA-N

grade

pharmaceutical primary standard

API family

copolymers, butylated methacrylate copolymer

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Basic butylated methacrylate copolyme EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

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Johanna Eisele et al.
Regulatory toxicology and pharmacology : RTP, 61(1), 32-43 (2011-06-28)
Basic Methacrylate Copolymer is a fully polymerised cationic copolymer with taste-masking and moisture protection properties. It is used as a pharmaceutical excipient and has potential use as a glazing/coating agent to solid food supplements. This article describes available information on
L S Ranzani et al.
Drug development and industrial pharmacy, 37(6), 694-701 (2011-01-14)
The aim of the present work was to investigate in vitro dissolution properties of three binary solid solutions prepared by a hot-melt extrusion (HME) process with vinyl pirrolidone--vinyl acetate copolymer (Kollidon VA 64), ethyl acrylate, methyl methacrylate polymer (Eudragit E)
Takatsune Yoshida et al.
International journal of pharmaceutics, 428(1-2), 18-24 (2012-03-13)
The aim of this study was to investigate the effect of Eudragit E/HCl (E-SD) on the reprecipitation of a poorly water-soluble drug, tacrolimus. To evaluate the inhibition of reprecipitation of E-SD, reprecipitation studies on tacrolimus were conducted using a dissolution
Tatiane Pereira de Souza et al.
AAPS PharmSciTech, 8(2), Article 34-Article 34 (2007-07-12)
The aim of this study was to investigate the feasibility of using Eudragit E as a granulating agent for a spray-dried extract from Phyllanthus niruri to obtain tablets containing a high dose of this product. The granules were developed by
M-S Kim
Drug research, 63(6), 326-330 (2013-03-26)
The present study sought to evaluate the pharmacokinetics of dutasteride-loaded Eudragit E nanoparticle in rats. In addition, the study investigated the effect of increasing drug load on the in vitro solubility and dissolution behavior of dutasteride together with its in

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